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Nature 435, 155-156 (12 May 2005) | doi:10.1038/435155a; Published online 11 May 2005

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Developmental biology:  Asymmetrical threat averted

Eran Hornstein1 & Clifford J. Tabin1

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The somites are embryonic elements that give rise to the muscles, skeleton and some skin layers of the trunk. They form in a symmetrical fashion, but to do so they must be shielded from asymmetrical cues.

The human body looks deceptively symmetrical from the outside. In contrast to this external symmetry, our internal organs are in an asymmetrical, yet reproducible, arrangement.

  1. Eran Hornstein and Clifford J. Tabin are in the Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
    Email: tabin@genetics.med.harvard.edu

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