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Brief Communications
Nature 435, 42 (5 May 2005) | doi:10.1038/435042a; Published online 4 May 2005
Biochemistry: A cadmium enzyme from a marine diatom
Todd W. Lane1, Mak A. Saito2, Graham N. George3, Ingrid J. Pickering3, Roger C. Prince4 & François M. M. Morel5
Abstract
The ocean biota contains a vast reservoir of genomic diversity1. Here we present the sequence and preliminary characterization of a protein that is a cadmium-containing carbonic anhydrase from the marine diatom Thalassiosira weissflogii. The existence of a cadmium enzyme in marine phytoplankton may indicate that there is a unique selection pressure for metalloenzymes in the marine environment2, and our discovery provides a long-awaited explanation for the nutrient-like behaviour of cadmium in the oceans3.
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