Supplementary information

From the following article:

Hypothalamic KATP channels control hepatic glucose production

Alessandro Pocai, Tony K. T. Lam, Roger Gutierrez-Juarez, Silvana Obici, Gary J. Schwartz, Joseph Bryan, Lydia Aguilar-Bryan & Luciano Rossetti

Nature 434, 1026-1031(21 April 2005)

doi:10.1038/nature03439

BACK TO ARTICLE
Download plugins and applications

Supplementary Figures S1-S3

Supplementary Figure S1 shows that the activation of hypothalamic KATP channels lowers plasma glucose through inhibition of GP. Supplementary Figure S2 details the expression of SUR mRNA within the hypothalamus and effect of ICV insulin on glucose kinetics. Supplementary Figure S3 demonstrates that the hepatic vagus and activation of hypothalamic KATP channels are required for the effect of physiological hyperinsulinemia on GP.

Download PDF file (1006KB)

Supplementary Figure Legends

This file contains Supplementary Figure Legends for Supplementary Figures S1-S3.

Download Word file (27KB)

Supplementary Tables S1-S8

This file contain the Supplementary Tables with metabolic parameters before and during the clamp and the specific activities of substrates used to calculate the hepatic glucose fluxes.

Download Word file (124KB)

BACK TO ARTICLE

DOWNLOAD BROWSER PLUGINS AND OTHER APPLICATIONS

Movie files

PDF douments

Text documents

PostScript documents

Flash movies

Audio files

Chemical structures

Mathematica

Microarray

Compressed Stuff files

Compressed Zip files

Systems Biology Markup Language files (SBML)

Chemical Markup language files (CML)

BACK TO ARTICLE