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Editorial

Wanted: social entrepreneurs p941

Scientists-turned-entrepreneurs are resuscitating the research and development of drugs for neglected diseases. Researchers, administrators and funders should contribute their expertise to help these initiatives — or set up their own.

doi: 10.1038/434941a


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News

Heightened security after flu scare sparks biosafety debate p943

Pandemic strain distributed to 6,000 labs in 19 countries

Erika Check

doi: 10.1038/434943a


Conclave kindles hope for bioethical reform p944

New Pope must wrestle with AIDS and biomedical advances

Declan Butler

doi: 10.1038/nature03654


Nobel laureate triumphs over loss of arm and returns to lab p945

Physics pioneer Eric Cornell makes light of disability

Kendall Powell

doi: 10.1038/434945a


Ecologist sues for lost tenure following transgene quarrel p945

Berkeley faces more unrest over biotech links

Rex Dalton

doi: 10.1038/434945b


Marburg workers battle to win trust of locals p946

Efforts to contain Angolan virus outbreak hit by violence

Emma Marris

doi: 10.1038/434946a


Computer conference welcomes gobbledegook paper p946

Researchers vent feelings through spoof submissions

Philip Ball

doi: 10.1038/nature03653


NASA boss takes the helm and launches plans for the future p947

Astronauts may service Hubble Telescope, after all

Tony Reichhardt

doi: 10.1038/434947a


Scientists speak out in search of fame and fortune p947

Reality TV meets science in London auditions

Jim Giles

doi: 10.1038/434947b


news in brief p948

doi: 10.1038/434948a


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News Features

Image manipulation:  CSI: cell biology p952

Digital photography and image-manipulation software allow biologists to tweak their data as never before. But there's a fine line between acceptable enhancements and scientific misconduct. Helen Pearson investigates.

doi: 10.1038/434952a

See also: Editor's summary


Animal behaviour:  When robots go wild p954

A steady stream of mechanical animals is marching out of the lab into the field. Jonathan Knight tunes in to see how these motorized models can expose what makes real creatures behave the way they do.

doi: 10.1038/434954a


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Correspondence

Who's helping to bring science to the people? p956

With student numbers falling, we need more researchers to do public-outreach work.

Pablo Jensen

doi: 10.1038/434956a


Reviewers not attached to online submission p956

Steve Donovan

doi: 10.1038/434956b


Funding shouldn't rely on competing death tolls p956

David Hilbert

doi: 10.1038/434956c


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Books and Arts

Seeds of discord p957

A useful, though partial, survey of how we breed the plants we eat.

Margaret E. Smith reviews Mendel in the Kitchen: A Scientist's View of Genetically Modified Foods by Nina Fedoroff and Nancy Marie Brown

doi: 10.1038/434957a


Admitting sympathy beyond species p958

Juliet Clutton-Brock reviews Thinking with Animals: New Perspectives on Anthropomorphism

doi: 10.1038/434958a


Science and culture: Polluting utopia p959

The idyllic reputation of a lost island community may not be wholly deserved.

Andy Meharg reviews

doi: 10.1038/434959a


The descent of Mount Petroleum p960

Robert K. Kaufmann reviews Beyond Oil: The View from Hubbert's Peak by Kenneth S. Deffeyes

doi: 10.1038/434960a


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Essay

Concept

Striking a chord p961

Landscapes: when perturbed by climatic and tectonic changes, landscapes resonate with a range of frequencies.

Philip Allen

doi: 10.1038/434961a


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News and Views

Earth science:  Cracking the Himalaya p963

The collision of India with Asia causes large earthquakes and active faults along the southern margin of the Himalaya. But has localized erosion by monsoon rains created new faults in the interior of the range?

Douglas W. Burbank

doi: 10.1038/434963a


Metabolism:  A higher power for insulin p965

Glucose output from the liver is tightly regulated by insulin. But insulin holds sway over more than the liver — an unappreciated circuit in glucose control involves the opening of ion channels in the brain.

Fiona M. Gribble

doi: 10.1038/434965a

See also: Editor's summary


100 and 50 years ago p966

doi: 10.1038/434966a


Techniques:  NMR on a chip p966

If a nanoscale gallium arsenide structure is excited with an oscillating magnetic field, superpositions of nuclear spin states can be created and detected electrically. Quantum computing could be the beneficiary.

Robert Tycko

doi: 10.1038/434966b

See also: Editor's summary


Plant biology:  Scented story p967

Amanda Tromans

doi: 10.1038/434967a


Neurobiology:  Sculpted by competition p969

Neuronal competition helps connections to form in the brain: the branches of less active neurons are more likely to retract — and, it now seems, less likely to grow — than those of their more active neighbours.

Ole Petter Ottersen

doi: 10.1038/434969a

See also: Editor's summary


Obituary:  Hans A. Bethe (1906−2005) p970

Kurt Gottfried and Edwin E. Salpeter

doi: 10.1038/434970a


Research highlights p972

doi: 10.1038/434972a


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Brief Communications

Insect behaviour:  Arboreal ants build traps to capture prey p973

Tiny ants construct an elaborate ambush to immobilize and kill much larger insects.

Alain Dejean, Pascal Jean Solano, Julien Ayroles, Bruno Corbara and Jérôme Orivel

doi: 10.1038/434973a

See also: Editor's summary


Predation:  Prey plumage adaptation against falcon attack p973

Alberto Palleroni, Cory T. Miller, Marc Hauser and Peter Marler

doi: 10.1038/434973b


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Review Article

Centennial-scale climate cooling with a sudden cold event around 8,200 years ago p975

Eelco J. Rohling and Heiko Pälike

doi: 10.1038/nature03421

See also: Editor's summary


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Articles

The genome sequence of the rice blast fungus Magnaporthe grisea p980

Ralph A. Dean, Nicholas J. Talbot, Daniel J. Ebbole, Mark L. Farman, Thomas K. Mitchell, Marc J. Orbach, Michael Thon, Resham Kulkarni, Jin-Rong Xu, Huaqin Pan, Nick D. Read, Yong-Hwan Lee, Ignazio Carbone, Doug Brown, Yeon Yee Oh, Nicole Donofrio, Jun Seop Jeong, Darren M. Soanes, Slavica Djonovic, Elena Kolomiets, Cathryn Rehmeyer, Weixi Li, Michael Harding, Soonok Kim, Marc-Henri Lebrun, Heidi Bohnert, Sean Coughlan, Jonathan Butler, Sarah Calvo, Li-Jun Ma, Robert Nicol, Seth Purcell, Chad Nusbaum, James E. Galagan and Bruce W. Birren

doi: 10.1038/nature03449

See also: Editor's summary


Molecular mechanisms of kinetochore capture by spindle microtubules p987

Kozo Tanaka, Naomi Mukae, Hilary Dewar, Mark van Breugel, Euan K. James, Alan R. Prescott, Claude Antony and Tomoyuki U. Tanaka

doi: 10.1038/nature03483


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Letters to Nature

No high-mass protostars in the silhouette young stellar object M17-SO1 p995

Shigeyuki Sako, Takuya Yamashita, Hirokazu Kataza, Takashi Miyata, Yoshiko K. Okamoto, Mitsuhiko Honda, Takuya Fujiyoshi, Hiroshi Terada, Takeshi Kamazaki, Zhibo Jiang, Tomoyuki Hanawa and Takashi Onaka

doi: 10.1038/nature03471


Chronology of the early Solar System from chondrule-bearing calcium-aluminium-rich inclusions p998

Alexander N. Krot, Hisayoshi Yurimoto, Ian D. Hutcheon and Glenn J. MacPherson

doi: 10.1038/nature03470


Controlled multiple quantum coherences of nuclear spins in a nanometre-scale device p1001

Go Yusa, Koji Muraki, Kei Takashina, Katsushi Hashimoto and Yoshiro Hirayama

doi: 10.1038/nature03456

See also: Editor's summary | News and Views by Tycko


Seasonal prediction of hurricane activity reaching the coast of the United States p1005

Mark A. Saunders and Adam S. Lea

doi: 10.1038/nature03454

See also: Editor's summary


Active out-of-sequence thrust faulting in the central Nepalese Himalaya p1008

Cameron Wobus, Arjun Heimsath, Kelin Whipple and Kip Hodges

doi: 10.1038/nature03499

See also: News and Views by Burbank


Geobiology of a microbial endolithic community in the Yellowstone geothermal environment p1011

Jeffrey J. Walker, John R. Spear and Norman R. Pace

doi: 10.1038/nature03447

See also: Editor's summary


Species diversity can drive speciation p1015

Brent C. Emerson and Niclas Kolm

doi: 10.1038/nature03450

See also: Editor's summary


Sexual reproduction between partners of the same mating type in Cryptococcus neoformans p1017

Xiaorong Lin, Christina M. Hull and Joseph Heitman

doi: 10.1038/nature03448


Regulation of axon growth in vivo by activity-based competition p1022

Jackie Yuanyuan Hua, Matthew C. Smear, Herwig Baier and Stephen J. Smith

doi: 10.1038/nature03409

See also: Editor's summary | News and Views by Ottersen


Hypothalamic KATP channels control hepatic glucose production p1026

Alessandro Pocai, Tony K. T. Lam, Roger Gutierrez-Juarez, Silvana Obici, Gary J. Schwartz, Joseph Bryan, Lydia Aguilar-Bryan and Luciano Rossetti

doi: 10.1038/nature03439

See also: Editor's summary | News and Views by Gribble


Sox2 is required for sensory organ development in the mammalian inner ear p1031

Amy E. Kiernan, Anna L. Pelling, Keith K. H. Leung, Anna S. P. Tang, Donald M. Bell, Charles Tease, Robin Lovell-Badge, Karen P. Steel and Kathryn S. E. Cheah

doi: 10.1038/nature03487


Spatiotemporal regulation of MyD88−IRF-7 signalling for robust type-I interferon induction p1035

Kenya Honda, Yusuke Ohba, Hideyuki Yanai, Hideo Negishi, Tatsuaki Mizutani, Akinori Takaoka, Choji Taya and Tadatsugu Taniguchi

doi: 10.1038/nature03547


Visualizing the mechanical activation of Src p1040

Yingxiao Wang, Elliot L. Botvinick, Yihua Zhao, Michael W. Berns, Shunichi Usami, Roger Y. Tsien and Shu Chien

doi: 10.1038/nature03469


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Naturejobs

Prospects

Breaking the bottleneck p1047

Paul Smaglik

doi: 10.1038/nj7036-1047a


Postdocs

Counting the cost p1048

Budgeting wisely can be critical to a young lab's early success. Kendall Powell finds out how to stretch funds for maximum effect.

Kendall Powell

doi: 10.1038/nj7036-1048a


Career View

Graduate Journal:  First−night nerves p1050

Anne Margaret Lee

doi: 10.1038/nj7036-1050a


Scientists & Societies p1050

Keith Micoli

doi: 10.1038/nj7036-1050b


Movers p1050

doi: 10.1038/nj7036-1050c


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Futures

Oscar night, 2054 p1052

A collection of heavenly bodies.

Syne Mitchell

doi: 10.1038/4341052a


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