Table of contents
Volume 434 Number 7036 pp941-1052
In this issue (21 April 2005)
Also this week
Editorial
Wanted: social entrepreneurs p941
Scientists-turned-entrepreneurs are resuscitating the research and development of drugs for neglected diseases. Researchers, administrators and funders should contribute their expertise to help these initiatives — or set up their own.
doi: 10.1038/434941a
News
Heightened security after flu scare sparks biosafety debate p943
Pandemic strain distributed to 6,000 labs in 19 countries
Erika Check
doi: 10.1038/434943a
Conclave kindles hope for bioethical reform p944
New Pope must wrestle with AIDS and biomedical advances
Declan Butler
doi: 10.1038/nature03654
Nobel laureate triumphs over loss of arm and returns to lab p945
Physics pioneer Eric Cornell makes light of disability
Kendall Powell
doi: 10.1038/434945a
Ecologist sues for lost tenure following transgene quarrel p945
Berkeley faces more unrest over biotech links
Rex Dalton
doi: 10.1038/434945b
Marburg workers battle to win trust of locals p946
Efforts to contain Angolan virus outbreak hit by violence
Emma Marris
doi: 10.1038/434946a
Computer conference welcomes gobbledegook paper p946
Researchers vent feelings through spoof submissions
Philip Ball
doi: 10.1038/nature03653
NASA boss takes the helm and launches plans for the future p947
Astronauts may service Hubble Telescope, after all
Tony Reichhardt
doi: 10.1038/434947a
Scientists speak out in search of fame and fortune p947
Reality TV meets science in London auditions
Jim Giles
doi: 10.1038/434947b
News Features
Image manipulation: CSI: cell biology p952
Digital photography and image-manipulation software allow biologists to tweak their data as never before. But there's a fine line between acceptable enhancements and scientific misconduct. Helen Pearson investigates.
doi: 10.1038/434952a
See also: Editor's summary
Animal behaviour: When robots go wild p954
A steady stream of mechanical animals is marching out of the lab into the field. Jonathan Knight tunes in to see how these motorized models can expose what makes real creatures behave the way they do.
doi: 10.1038/434954a
Correspondence
Who's helping to bring science to the people? p956
With student numbers falling, we need more researchers to do public-outreach work.
Pablo Jensen
doi: 10.1038/434956a
Reviewers not attached to online submission p956
Steve Donovan
doi: 10.1038/434956b
Funding shouldn't rely on competing death tolls p956
David Hilbert
doi: 10.1038/434956c
Books and Arts
Seeds of discord p957
A useful, though partial, survey of how we breed the plants we eat.
Margaret E. Smith reviews Mendel in the Kitchen: A Scientist's View of Genetically Modified Foods by Nina Fedoroff and Nancy Marie Brown
doi: 10.1038/434957a
Admitting sympathy beyond species p958
Juliet Clutton-Brock reviews Thinking with Animals: New Perspectives on Anthropomorphism
doi: 10.1038/434958a
Science and culture: Polluting utopia p959
The idyllic reputation of a lost island community may not be wholly deserved.
Andy Meharg reviews
doi: 10.1038/434959a
The descent of Mount Petroleum p960
Robert K. Kaufmann reviews Beyond Oil: The View from Hubbert's Peak by Kenneth S. Deffeyes
doi: 10.1038/434960a
Essay
ConceptStriking a chord p961
Landscapes: when perturbed by climatic and tectonic changes, landscapes resonate with a range of frequencies.
Philip Allen
doi: 10.1038/434961a
News and Views
Earth science: Cracking the Himalaya p963
The collision of India with Asia causes large earthquakes and active faults along the southern margin of the Himalaya. But has localized erosion by monsoon rains created new faults in the interior of the range?
Douglas W. Burbank
doi: 10.1038/434963a
Metabolism: A higher power for insulin p965
Glucose output from the liver is tightly regulated by insulin. But insulin holds sway over more than the liver — an unappreciated circuit in glucose control involves the opening of ion channels in the brain.
Fiona M. Gribble
doi: 10.1038/434965a
See also: Editor's summary
100 and 50 years ago p966
doi: 10.1038/434966a
Techniques: NMR on a chip p966
If a nanoscale gallium arsenide structure is excited with an oscillating magnetic field, superpositions of nuclear spin states can be created and detected electrically. Quantum computing could be the beneficiary.
Robert Tycko
doi: 10.1038/434966b
See also: Editor's summary
Plant biology: Scented story p967
Amanda Tromans
doi: 10.1038/434967a
Neurobiology: Sculpted by competition p969
Neuronal competition helps connections to form in the brain: the branches of less active neurons are more likely to retract — and, it now seems, less likely to grow — than those of their more active neighbours.
Ole Petter Ottersen
doi: 10.1038/434969a
See also: Editor's summary
Obituary: Hans A. Bethe (1906−2005) p970
Kurt Gottfried and Edwin E. Salpeter
doi: 10.1038/434970a
Brief Communications
Insect behaviour: Arboreal ants build traps to capture prey p973
Tiny ants construct an elaborate ambush to immobilize and kill much larger insects.
Alain Dejean, Pascal Jean Solano, Julien Ayroles, Bruno Corbara and Jérôme Orivel
doi: 10.1038/434973a
First paragraph | Full Text | PDF (212K) | Supplementary information
See also: Editor's summary
Predation: Prey plumage adaptation against falcon attack p973
Alberto Palleroni, Cory T. Miller, Marc Hauser and Peter Marler
doi: 10.1038/434973b
First paragraph | Full Text | PDF (310K) | Supplementary information
Review Article
Centennial-scale climate cooling with a sudden cold event around 8,200 years ago p975
Eelco J. Rohling and Heiko Pälike
doi: 10.1038/nature03421
Abstract | Full Text | PDF (391K) | Supplementary information
See also: Editor's summary
Articles
The genome sequence of the rice blast fungus Magnaporthe grisea p980
Ralph A. Dean, Nicholas J. Talbot, Daniel J. Ebbole, Mark L. Farman, Thomas K. Mitchell, Marc J. Orbach, Michael Thon, Resham Kulkarni, Jin-Rong Xu, Huaqin Pan, Nick D. Read, Yong-Hwan Lee, Ignazio Carbone, Doug Brown, Yeon Yee Oh, Nicole Donofrio, Jun Seop Jeong, Darren M. Soanes, Slavica Djonovic, Elena Kolomiets, Cathryn Rehmeyer, Weixi Li, Michael Harding, Soonok Kim, Marc-Henri Lebrun, Heidi Bohnert, Sean Coughlan, Jonathan Butler, Sarah Calvo, Li-Jun Ma, Robert Nicol, Seth Purcell, Chad Nusbaum, James E. Galagan and Bruce W. Birren
doi: 10.1038/nature03449
Abstract | Full Text | PDF (468K) | Supplementary information
See also: Editor's summary
Molecular mechanisms of kinetochore capture by spindle microtubules p987
Kozo Tanaka, Naomi Mukae, Hilary Dewar, Mark van Breugel, Euan K. James, Alan R. Prescott, Claude Antony and Tomoyuki U. Tanaka
doi: 10.1038/nature03483
Abstract | Full Text | PDF (729K) | Supplementary information
Letters to Nature
No high-mass protostars in the silhouette young stellar object M17-SO1 p995
Shigeyuki Sako, Takuya Yamashita, Hirokazu Kataza, Takashi Miyata, Yoshiko K. Okamoto, Mitsuhiko Honda, Takuya Fujiyoshi, Hiroshi Terada, Takeshi Kamazaki, Zhibo Jiang, Tomoyuki Hanawa and Takashi Onaka
doi: 10.1038/nature03471
First paragraph | Full Text | PDF (292K) | Supplementary information
Chronology of the early Solar System from chondrule-bearing calcium-aluminium-rich inclusions p998
Alexander N. Krot, Hisayoshi Yurimoto, Ian D. Hutcheon and Glenn J. MacPherson
doi: 10.1038/nature03470
First paragraph | Full Text | PDF (404K) | Supplementary information
Controlled multiple quantum coherences of nuclear spins in a nanometre-scale device p1001
Go Yusa, Koji Muraki, Kei Takashina, Katsushi Hashimoto and Yoshiro Hirayama
doi: 10.1038/nature03456
First paragraph | Full Text | PDF (417K)
See also: Editor's summary | News and Views by Tycko
Seasonal prediction of hurricane activity reaching the coast of the United States p1005
Mark A. Saunders and Adam S. Lea
doi: 10.1038/nature03454
First paragraph | Full Text | PDF (361K)
See also: Editor's summary
Active out-of-sequence thrust faulting in the central Nepalese Himalaya p1008
Cameron Wobus, Arjun Heimsath, Kelin Whipple and Kip Hodges
doi: 10.1038/nature03499
First paragraph | Full Text | PDF (231K)
See also: News and Views by Burbank
Geobiology of a microbial endolithic community in the Yellowstone geothermal environment p1011
Jeffrey J. Walker, John R. Spear and Norman R. Pace
doi: 10.1038/nature03447
First paragraph | Full Text | PDF (297K)
See also: Editor's summary
Species diversity can drive speciation p1015
Brent C. Emerson and Niclas Kolm
doi: 10.1038/nature03450
First paragraph | Full Text | PDF (164K) | Supplementary information
See also: Editor's summary
Sexual reproduction between partners of the same mating type in Cryptococcus neoformans p1017
Xiaorong Lin, Christina M. Hull and Joseph Heitman
doi: 10.1038/nature03448
First paragraph | Full Text | PDF (279K) | Supplementary information
Regulation of axon growth in vivo by activity-based competition p1022
Jackie Yuanyuan Hua, Matthew C. Smear, Herwig Baier and Stephen J. Smith
doi: 10.1038/nature03409
First paragraph | Full Text | PDF (386K) | Supplementary information
See also: Editor's summary | News and Views by Ottersen
Hypothalamic KATP channels control hepatic glucose production p1026
Alessandro Pocai, Tony K. T. Lam, Roger Gutierrez-Juarez, Silvana Obici, Gary J. Schwartz, Joseph Bryan, Lydia Aguilar-Bryan and Luciano Rossetti
doi: 10.1038/nature03439
First paragraph | Full Text | PDF (412K) | Supplementary information
See also: Editor's summary | News and Views by Gribble
Sox2 is required for sensory organ development in the mammalian inner ear p1031
Amy E. Kiernan, Anna L. Pelling, Keith K. H. Leung, Anna S. P. Tang, Donald M. Bell, Charles Tease, Robin Lovell-Badge, Karen P. Steel and Kathryn S. E. Cheah
doi: 10.1038/nature03487
First paragraph | Full Text | PDF (316K) | Supplementary information
Spatiotemporal regulation of MyD88−IRF-7 signalling for robust type-I interferon induction p1035
Kenya Honda, Yusuke Ohba, Hideyuki Yanai, Hideo Negishi, Tatsuaki Mizutani, Akinori Takaoka, Choji Taya and Tadatsugu Taniguchi
doi: 10.1038/nature03547
First paragraph | Full Text | PDF (425K) | Supplementary information
Visualizing the mechanical activation of Src p1040
Yingxiao Wang, Elliot L. Botvinick, Yihua Zhao, Michael W. Berns, Shunichi Usami, Roger Y. Tsien and Shu Chien
doi: 10.1038/nature03469
First paragraph | Full Text | PDF (511K) | Supplementary information
Naturejobs
ProspectsBreaking the bottleneck p1047
Paul Smaglik
doi: 10.1038/nj7036-1047a
Postdocs
Counting the cost p1048
Budgeting wisely can be critical to a young lab's early success. Kendall Powell finds out how to stretch funds for maximum effect.
Kendall Powell
doi: 10.1038/nj7036-1048a
Career View
Graduate Journal: First−night nerves p1050
Anne Margaret Lee
doi: 10.1038/nj7036-1050a
Scientists & Societies p1050
Keith Micoli
doi: 10.1038/nj7036-1050b
Movers p1050
doi: 10.1038/nj7036-1050c
Futures
Oscar night, 2054 p1052
A collection of heavenly bodies.
Syne Mitchell
doi: 10.1038/4341052a