FIGURE 2. DSB formation and repair after exposure to PARP inhibitor.
From the following article:
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
Hannah Farmer, Nuala McCabe, Christopher J. Lord, Andrew N. J. Tutt, Damian A. Johnson, Tobias B. Richardson, Manuela Santarosa, Krystyna J. Dillon, Ian Hickson, Charlotte Knights, Niall M. B. Martin, Stephen P. Jackson, Graeme C. M. Smith and Alan Ashworth
Nature 434, 917-921(14 April 2005)
doi:10.1038/nature03445
a, ES cells were exposed to 10 
M KU0058684 or vehicle for 48 h. Nuclei are shown in blue and 
-H2AX foci in red. b, ES cells were exposed to 10 M KU0058684 or vehicle for 48 h. Nuclei are shown in blue and RAD51 foci in red. Scale bar, 10 m.
