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Nature 434, 797 (7 April 2005) | doi:10.1038/434797a; Published online 6 April 2005

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Automation in two dimensions

Microfluidic systems have taken over from two-dimensional (2D) gel electrophoresis techniques in some areas of protein separation and analysis, but the established methods are far from dead. Even though they can be slower and messier, the tried and tested 2D protocols still offer some advantages, especially if automation can take out most of the hassle.

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