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Nature 434, 715-716 (7 April 2005) | doi:10.1038/434715a; Published online 6 April 2005
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Developmental biology: Reproduction in clusters
François Spitz1 & Denis Duboule1
Abstract
Homeobox genes have some quirky features: they huddle together and tend to be expressed in the order that they appear in their cluster. A new cluster, specific to reproductive development, has now been discovered.
The survival of animal species depends upon the proper development of germ cells: oocytes and sperm. In mammals, this process is tightly coordinated with the development of non-reproductive cells nearby, such as Sertoli cells, which nourish developing sperm cells1.
- François Spitz and Denis Duboule are at the National Research Centre 'Frontiers in Genetics', and the Department of Zoology and Animal Biology, University of Geneva, Sciences III, Quai Ernest Ansermet 30, 1211 Geneva 4, Switzerland.
e-mail: Email: Denis.Duboule@zoo.unige.ch
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