FIGURE 2. The cannabinoid receptor CB2 is expressed on macrophages and T lymphocytes within atherosclerotic plaques of ApoE-/- mice.
From the following article:
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
Sabine Steffens, Niels R. Veillard, Claire Arnaud, Graziano Pelli, Fabienne Burger, Christian Staub, Andreas Zimmer, Jean-Louis Frossard and François Mach
Nature 434, 782-786(7 April 2005)
doi:10.1038/nature03389
Shown are representative photomicrographs of ApoE-/- mouse aortic root cryosections, with the lumen of the artery at the right side of each photo. Immunofluorescence double-labelling was performed for CB2 receptors (green) and a cell-specific marker (red) for macrophages (M
) or T lymphocytes (CD4). Nuclei were stained in blue with DAPI. Analysis of atheroma from 4 different mice showed similar results.
