Supplementary information

From the following article:

Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA

Anirban Banerjee, Wei Yang, Martin Karplus and Gregory L. Verdine

Nature 434, 612-618(31 March 2005)

doi:10.1038/nature03458

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Supplementary Table S1

Data collection and model statistics.

Supplementary Figure Legends

Figure captions for Supplementary Figures S1-S4.

Supplementary Methods

Additional details on computational methods and data collection and structure solution.

Supplementary Figure S1

Structural validation of the trapping strategy and crosslinking biochemistry.

Supplementary Figure S2

Electron density map around the G in the exo- site and the crosslinked C in the G-complex.

Supplementary Figure S3

Structural representations of the carbonyl of Gly42 and different nucleobases used in this study.

Supplementary Figure S4

Electron density maps around the analogs in the crosslinked complexes.

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