The p53 protein is notorious for its involvement in many cancers. Studies in mice are helping to clarify how mutations in the human p53 protein produce a wide variety of tumours.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
TP53 status and taxane-platinum versus platinum-based therapy in ovarian cancer patients: A non-randomized retrospective study
BMC Cancer Open Access 29 January 2008
-
High resolution melting for mutation scanning of TP53exons 5–8
BMC Cancer Open Access 31 August 2007
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Olive, K. P. et al. Cell 119, 847–860 (2004).
Lang, G. A. et al. Cell 119, 861–872 (2004).
Ryan, K. M., Phillips, A. C. & Vousden, K. H. Curr. Opin. Cell Biol. 13, 332–337 (2001).
Hofseth, L. J., Hussain, S. P. & Harris, C. C. Trends Pharmacol. Sci. 25, 177–181 (2004).
Greenblatt, M. S., Bennett, W. P., Hollstein, M. & Harris, C. C. Cancer Res. 54, 4855–4878 (1994).
Sigal, A. & Rotter, V. Cancer Res. 60, 6788–6793 (2000).
Varley, J. M. Hum. Mutat. 21, 313–320 (2003); Erratum Hum. Mutat. 21, 551 (2003).
Evans, S. C. & Lozano, G. Mol. Med. Today 3, 390–395 (1997).
Melino, G., Lu, X., Gasco, M., Crook, T. & Knight, R. A. Trends Biochem. Sci. 28, 663–670 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Dyke, T. Sense out of missense. Nature 434, 287–288 (2005). https://doi.org/10.1038/434287a
Published:
Issue Date:
DOI: https://doi.org/10.1038/434287a
