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Nature 434, 127 (10 March 2005) | doi:10.1038/434127b; Published online 9 March 2005

Gene-therapy trials to restart following cancer risk review

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US researchers to trial gene therapy on children with SCID.

Gene-therapy trials for children suffering from severe combined immunodeficiency disease (SCID) are set to resume in the United States, despite another cancer case in a French trial of the technique.On 4 March, an advisory meeting in Rockville, Maryland, heard evidence that the cancer risk exposed by the French trial may be specific to one form of the disease, known as X-linked SCID.

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