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News and Views
Nature 434, 152-153 (10 March 2005) | doi:10.1038/434152a; Published online 9 March 2005
Developmental biology: Sperm–egg fusion unscrambled
Richard Schultz1 & Carmen Williams1
Abstract
The identity of the sperm molecules that are involved in fusion with an egg's membrane has eluded biologists. Will Izumo, a protein named after the Japanese shrine to marriage, bring harmony to the field?
In the life history of sexually reproducing organisms, fertilization is a defining event. In mammals, sperm and egg have a limited lifespan once present in the female reproductive tract.
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