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News and Views
Nature 433, 585-587 (10 February 2005) | doi:10.1038/433585a; Published online 9 February 2005
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Cardiology: Solace for the broken-hearted?
Christine L. Mummery1
Abstract
The heart was thought to lack the capacity to regenerate after injury. But the identification of cells that can divide and mature into heart muscle suggests that the heart has repair mechanisms after all.
Heart attacks are fatal when they damage more than a quarter of the heart's left ventricle — killing off about 109 heart cells in the process. In patients who survive less severe attacks, dead heart cells are replaced by cells from the connective tissue called fibroblasts, which divide and migrate into the damaged area to form scar tissue.
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Christine L. Mummery is in the Hubrecht Laboratory and the Interuniversity Cardiology Institute of the Netherlands, University Medical Centre, Uppsalalaan 8, 3584 CT
Utrecht, The Netherlands.
e-mail: Email: christin@niob.knaw.nl
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