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Cell biology

Holding sisters for repair

When a DNA molecule breaks, its complementary copy can be used as a template for repair. A familiar protein complex is recruited to the damaged site, keeping it close to the undamaged copy.

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Figure 1: Local recruitment of cohesin for DNA repair.

References

  1. Ünal, E. et al. Mol. Cell 16, 991–1002 (2004).

    Article  Google Scholar 

  2. Ström, L., Lindroos, H. B., Shirahige, K. & Sjögren, C. Mol. Cell 16, 1003–1015 (2004).

    Article  Google Scholar 

  3. Nasmyth, K. Annu. Rev. Genet. 35, 673–745 (2001).

    Article  CAS  Google Scholar 

  4. Birkenbihl, R. P. & Subramani, S. Nucl. Acids Res. 20, 6605–6611 (1992).

    Article  CAS  Google Scholar 

  5. Sjögren, C. & Nasmyth, K. Curr. Biol. 11, 991–995 (2001).

    Article  Google Scholar 

  6. Sonoda, E. et al. Dev. Cell 1, 759–770 (2001).

    Article  CAS  Google Scholar 

  7. Shroff, R. et al. Curr. Biol. 14, 1703–1711 (2004).

    Article  CAS  Google Scholar 

  8. Kim, J. S., Krasieva, T. B., LaMorte, V., Taylor, A. M. & Yokomori, K. J. Biol. Chem. 277, 45149–45153 (2002).

    Article  CAS  Google Scholar 

  9. Kim, S.-T., Xu, B. & Kastan, M. B. Genes Dev. 16, 560–570 (2002).

    Article  CAS  Google Scholar 

  10. Yazdi, P. T. et al. Genes Dev. 16, 571–582 (2002).

    Article  CAS  Google Scholar 

  11. Kitagawa, R., Bakkenist, C. J., McKinnon, P. J. & Kastan, M. B. Genes Dev. 18, 1423–1438 (2004).

    Article  CAS  Google Scholar 

  12. Nagao, K., Adachi, Y. & Yanagida, M. Nature 430, 1044–1048 (2004).

    Article  ADS  CAS  Google Scholar 

Download references

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Hirano, T. Holding sisters for repair. Nature 433, 467–468 (2005). https://doi.org/10.1038/433467a

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