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Nature 433, 203-204 (20 January 2005) | doi:10.1038/433203a; Published online 19 January 2005
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Molecular Biologists and Biochemists
- University of Minnesota
- Minnesota, USA
Postdoctoral Fellow - Computational Genomics - Team 78 – Ref: 80464
- Wellcome Trust Sanger Institute
- Hinxton, Cambridgeshire CB10 1, UK
Endocrinology: Fertility hormone in repose
James A. Dias1
Abstract
Egg and sperm development are triggered when follicle-stimulating hormone binds to its receptor. A three-dimensional structural snapshot reveals how the hormone slots into its receptor, and how specificity of binding is ensured.
Each year, around 20% of couples in the United States consult a fertility specialist because of problems with infertility. Many will seek help through assisted reproductive technologies1.
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James A. Dias is at the Wadsworth Center, New York State Department of Health, and in the Department of Biomedical Sciences, State University of New York at Albany, David Axelrod Institute, 120 New Scotland Avenue, Albany, New York
12208, USA.
e-mail: Email: james.dias@wadsworth.org
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RESEARCH
Structure of human follicle-stimulating hormone in complex with its receptorNature Article (20 Jan 2005)
Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificityThe EMBO Journal Article (01 Jun 2003)
Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificityThe EMBO Journal Article (01 Jun 2003)
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