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Endocrinology:  Fertility hormone in repose

James A. Dias1

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Egg and sperm development are triggered when follicle-stimulating hormone binds to its receptor. A three-dimensional structural snapshot reveals how the hormone slots into its receptor, and how specificity of binding is ensured.

Each year, around 20% of couples in the United States consult a fertility specialist because of problems with infertility. Many will seek help through assisted reproductive technologies1.

  1. James A. Dias is at the Wadsworth Center, New York State Department of Health, and in the Department of Biomedical Sciences, State University of New York at Albany, David Axelrod Institute, 120 New Scotland Avenue, Albany, New York 12208, USA.
    e-mail: Email: james.dias@wadsworth.org

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