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Nature 433, 26-27 (6 January 2005) | doi:10.1038/433026a; Published online 5 January 2005

Human immunodeficiency virus:  Nuclear RNA export unwound

Bryan R. Cullen1

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The ways in which HIV can subvert cellular processes for its own ends seem boundless. The latest discovery — a cellular enzyme that helps to export HIV RNA from the nucleus — reveals a possible drug target.

Gene expression is a multi-step process, the first stage of which is the production of a messenger RNA transcript of a gene. That mRNA is then used as a template to produce a protein.

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