Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I

doi:doi:10.1038/nature03179

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Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I

Jianhang Jia, Chao Tong, Bing Wang, Liping Luo and Jin Jiang

Nature 432, 1045-1050(23 December 2004)

doi:10.1038/nature03179

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Supplementary Figures

This file contains figures and legends for Supplementary Fig. S1 (rescuing smo mutant phenotypes by Smo variants), Fig. S2 (regulation of Smo cell surface accumulation by phosphorylation in S2 cells), Fig. S3 (cell surface accumulation of wild type Smo and Smo^SD123 in wing discs) and Fig. S4 (effects of overexpressing phosphorylation deficient forms of Smo on accumulation of wild type Smo in wing discs).

Supplementary Figures - Download Word file (3.04MB)

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