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From the following article:

Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I

Jianhang Jia, Chao Tong, Bing Wang, Liping Luo and Jin Jiang

Nature 432, 1045-1050(23 December 2004)

doi:10.1038/nature03179

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Positive regulation of Smo accumulation and Hh signalling by PKA and CKI.

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Figure 2

Phosphorylation of Smo by PKA and CKI.

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Figure 3

Hh signalling activity of Smo variants.

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Figure 4

Regulation of Smo cell-surface accumulation by phosphorylation and models for kinase regulation of Smo activity.

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