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Nature 432, 815-816 (16 December 2004) | doi:10.1038/432815a; Published online 15 December 2004
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Cell biology: Popping out of the nucleus
Abstract
Previous structural snapshots have provided insight into how proteins are imported into the cell nucleus. The structure of an export complex now completes the molecular picture of the nuclear transport cycle.
A notable stage in evolution was the compartmentalization of cells, producing the eukaryotic cell — the cell type found in organisms from fungi to humans. During this process, the genetic information became enclosed inside a nucleus, spatially separated from the rest of the cell.
- André Hoelz and Günter Blobel are in the Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.
Email: hoelza@mail.rockefeller.edu
Email: blobel@mail.rockefeller.edu
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