FIGURE 2. Comparison of theoretical viral load decay profiles with patient data.
From the following article:
Modelling how ribavirin improves interferon response rates in hepatitis C virus infection
Narendra M. Dixit, Jennifer E. Layden-Almer, Thomas J. Layden and Alan S. Perelson
Nature 432, 922-924(16 December 2004)
doi:10.1038/nature03153

Best-fit model predictions (representative) of viral load decay with
max = 1 (solid lines) and
max = 0 (dashed lines) compared with data (symbols) from patients 18 (a) and 35 (b)23. Parameters employed (Supplementary Table S1) were V0 = 8
106 ml-1, c = 3.8 d-1,
= 0.24 d-1,
= 0.982 and
= 4.3 h for both
max = 1 and
max = 0 (a) and V0 = 3.6
105 ml-1, c = 2.2 d-1,
= 0.16 d-1,
= 0.6 and
= 6.2 h for
max = 1, and V0 = 3.5
105 ml-1, c = 3.1 d-1,
= 0.31 d-1,
= 0.5 and
= 7.2 h for
max = 0 (b). Note that the two fits overlap in a.
