Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 432, 568-569 (2 December 2004) | doi:10.1038/432568a; Published online 1 December 2004
Open Innovation Challenges
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Assistant / Associate / Full Professor
- Northeastern University
- Boston, MA
Project Director, Nouabalé-Ndoki Park Project
- Wildlife Conservation Society
- Congo Republic
Cell biology: Clathrin's Achilles' ankle
Frances M. Brodsky1
Abstract
The protein clathrin forms lattice-like coats on transport vesicles that bud from cell membranes. High-resolution models of the lattice reveal interactions involved in its disassembly once the vesicles have formed.
Cells are busy places, with membrane traffic moving in all directions — from the cell surface to internal compartments and back again, and from one compartment to another. The transport vehicles are tiny, membrane-bound spheres called vesicles, which bud off from the membrane that encloses a compartment (or the cell itself), and fuse with a target membrane.
- Frances M. Brodsky is in the Departments of Biopharmaceutical Sciences, Pharmaceutical Chemistry, and Microbiology and Immunology, and the G. W. Hooper Foundation, University of California, San Francisco, California 94143-0552, USA.
Email: fmarbro@itsa.ucsf.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Surface versus Intracellular Polarization of Cortical CellsNature Letters to Editor (21 Oct 1967)
Parthenogenesis in a BeetleNature Letters to Editor (04 Sep 1879)
See all 15 matches for Research