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Nature 432, 564-567 (2 December 2004) | doi:10.1038/432564a; Published online 1 December 2004
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Cell division: The heart of the cycle
Abstract
To reproduce, cells must copy their genetic material and distribute the replicas into two daughter cells. A self-perpetuating molecular oscillator regulates periodic transitions between these two processes.
Good things come to those who wait — a maxim that is as true for cells as it is elsewhere in life. Dividing cells must wait until their DNA is completely duplicated before they can segregate the replicas.
- Jiri Lukas and Jiri Bartek are at the Danish Cancer Society, Institute of Cancer Biology, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.
Email: lukas@biobase.dk
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