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News and Views
Nature 432, 563-564 (2 December 2004) | doi:10.1038/432563a; Published online 1 December 2004
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Cytoskeleton: Spindle saga
Eric Karsenti1
Abstract
It's generally been thought that, during cell division, only proteins are necessary to assemble the machine that segregates chromosomes. But a new molecular requirement has been discovered.
Arguably the most striking structure a cell can produce is the spindle — a fine meshwork of filaments that carries out a fundamental task in cell division. Before one cell can make two, it must duplicate its DNA; the replicated chromosomes must then be separated and pulled to opposite poles of the cell, which splits into two.
- Eric Karsenti is at the European Molecular Biology Laboratory, Cell Biology and Biophysics Programme, Meyerhofstrasse 1, Heidelberg 69117, Germany.
Email: karsenti@embl-heidelberg.de
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