Table of contents
Volume 432 Number 7016 pp421-533
(this content only available online) indicates content that is available online only
Editorials
Conscience call p421
Nuclear proliferation remains a potent threat — and scientists' active engagement is essential if it is to be effectively addressed.
doi:10.1038/432421a
Google Nouveau p421
On the Internet, 2004 promises to be a vintage year for searching.
doi:10.1038/432421b
News
Science searches shift up a gear as Google starts Scholar engine p423
Search engine aimed at academics unveiled.
Declan Butler
doi:10.1038/432423a
Lean budget leaves scientists wanting more p424
US federal spending plans passed by Congress.
Geoff Brumfiel and Tony Reichhardt
doi:10.1038/432424a
NIH head stands firm over plans for open access p424
Director hits back at critics of free archive plan.
Meredith Wadman
doi:10.1038/432424b
Huge study of children aims to get the dirt on development p425
Project to unpick how biology and environment interact.
Erika Check
doi:10.1038/432425a
Report censures political screening of advisory boards p425
Candidates should not be asked about political beliefs, say authors
Geoff Brumfiel
doi:10.1038/432425b
Junior scientists are denied access to data, says survey p426
Young researchers face hurdles getting details of research results.
Rex Dalton
doi:10.1038/432426a
Summit calls for clear view of deposits in all biobanks p426
Coordination of tissue banks could aid biology.
Helen Pearson
doi:10.1038/432426b
Chemistry claim provokes strong reaction p427
Nobel laureate dispute made public.
Alison Abbott
doi:10.1038/432427a
Asian nations build bridges to bolster science p427
China and India agree to forge closer ties.
K. S. Jayaraman
doi:10.1038/432427b
News Feature
Nuclear proliferation special: We have the technology p432
The global spread of nuclear weapons is once again a major headache for world leaders. Geoff Brumfiel reports on efforts to put the genie back in the bottle.
doi:10.1038/432432a
Correspondence
Replacement therapy, not recreational tonic p439
Testosterone, widely used as a lifestyle drug, is a medicine and should be kept as such.
Richard D. Jones, T. Hugh Jones and Kevin S. Channer
doi:10.1038/432439a
DDT still has a role in the fight against malaria p439
Allan Schapira
doi:10.1038/432439b
Presidential candidates failed peer-review test p439
Robert Insall
doi:10.1038/432439c
Benveniste's reputation was not written in water p439
Bernard Rothhut
doi:10.1038/432439d
Commentary
Revisiting the Baruch Plan p441
Developing a realistic strategy to control the proliferation of nuclear arms.
doi:10.1038/432441a
Books and Arts
When greens see red p443
An environmental warning and call to curb consumerism.
Dick Taverne reviews Red Sky At Morning: America and the Crisis of the Global Environment by James Gustave Speth
doi:10.1038/432443a
Crossing the boundary p444
Christopher M. Dobson reviews Biological Physics: Energy, Information, Life by Philip Nelson
doi:10.1038/432444a
A stage of evolution p445
Laura Spinney reviews The Darwin Variations by Jean-François Peyret and Alain Prochiantz
doi:10.1038/432445a
Essay
Turning pointsCrazy, but correct p447
How a non-conformist theory beat scepticism and got into the textbooks.
Daniel E. Koshland, Jr
doi:10.1038/432447a
News and Views
Human behaviour: Don't lose your reputation p449
Collective action in large groups whose members are genetically unrelated is a distinguishing feature of the human species. Individual reputations may be a key to a satisfactory evolutionary explanation.
Ernst Fehr
doi:10.1038/432449a
Materials science: A 'bed of nails' on silicon p450
The future of electronics may rest on devices that integrate other semiconductors with silicon. A means of creating tiny semiconductor pillars on a silicon surface is now demonstrated.
Max G. Lagally and Robert H. Blick
doi:10.1038/432450a
Regenerative medicine: Prometheus unbound p451
The discovery of a protein that stimulates cell migration and survival in damaged mouse hearts suggests a potential new approach to the treatment of heart attacks.
Michael D. Schneider
doi:10.1038/432451a
Quantum information: Atomic recorder for light quanta p453
The quantum information carried by a faint laser pulse has been trapped in a gas of atoms. This 'quantum memory' paves the way for networks that transmit and process information in non-classical ways.
Jean-Michel Raimond
doi:10.1038/432453a
100 and 50 years ago p453
doi:10.1038/432453b
Evolutionary biology: Light on ancient photoreceptors p454
Early multicellular organisms had two distinct types of photoreceptor cells, apparently with different functions. How these cells combined to form modern eyes turns out to be a complicated story.
Thurston Lacalli
doi:10.1038/432454a
Nonlinear physics: Fresh breather p455
The direct observation of highly localized, stable, nonlinear excitations — known as discrete breathers — at the atomic level underscores their importance in physical phenomena at all scales.
David K. Campbell
doi:10.1038/432455a
Molecular biology: Termination by torpedo p456
The information encoded in our genes must be copied into messenger RNAs, which will programme the protein-synthesis machinery. New results support an intriguing mechanism for ending the copying process.
David Tollervey
doi:10.1038/432456a
Brief Communications
Water resources: Groundwater maintains dune landscape p459
A remote water source helps giant sand dunes to stand their ground in a windy desert.
Jian Sheng Chen, Ling Li, Ji Yang Wang, D. A. Barry, Xue Fen Sheng, Wei Zu Gu, Xia Zhao and Liang Chen
doi:10.1038/432459a
First paragraph | Full Text | PDF (216K) | Supplementary information
Palaeoclimate: Ocean tides and Heinrich events p460
Brian K. Arbic, Douglas R. MacAyeal, Jerry X. Mitrovica and Glenn A. Milne
doi:10.1038/432460a
First paragraph | Full Text | PDF (115K) | Supplementary information
Top of page
Brief Communications Arising
Palaeoclimatology: Archaean atmosphere and climate
James F. Kasting
doi:10.1038/nature03166
First paragraph | Full Text | PDF (67K)
Palaeoclimatology: Archaean palaeosols and Archaean air
Norman H. Sleep
doi:10.1038/nature03167
First paragraph | Full Text | PDF (81K)
Palaeoclimatology: Archaean palaeosols and Archaean air (reply)
Hiroshi Ohmoto and Yumiko Watanabe
doi:10.1038/nature03168
First paragraph | Full Text | PDF (77K)
Review
Neanderthals and the modern human colonization of Europe p461
Paul Mellars
doi:10.1038/nature03103
Abstract | Full Text | PDF (304K)
Articles
Thymosin 
4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair p466
Ildiko Bock-Marquette, Ankur Saxena, Michael D. White, J. Michael DiMaio and Deepak Srivastava
doi:10.1038/nature03000
Abstract | Full Text | PDF (451K) | Supplementary information
See also: News and Views by Schneider
Human DNA ligase I completely encircles and partially unwinds nicked DNA p473
John M. Pascal, Patrick J. O'Brien, Alan E. Tomkinson and Tom Ellenberger
doi:10.1038/nature03082
Abstract | Full Text | PDF (430K) | Supplementary information
Letters to Nature
The building blocks of planets within the 'terrestrial' region of protoplanetary disks p479
R. van Boekel, M. Min, Ch. Leinert, L.B.F.M. Waters, A. Richichi, O. Chesneau, C. Dominik, W. Jaffe, A. Dutrey, U. Graser, Th. Henning, J. de Jong, R. Köhler, A. de Koter, B. Lopez, F. Malbet, S. Morel, F. Paresce, G. Perrin, Th. Preibisch, F. Przygodda, M. Schöller and M. Wittkowski
doi:10.1038/nature03088
First paragraph | Full Text | PDF (258K) | Supplementary information
Experimental demonstration of quantum memory for light p482
Brian Julsgaard,
Jacob Sherson,
J. Ignacio Cirac,
Jaromír Fiurá
ek
and
Eugene S. Polzik
doi:10.1038/nature03064
First paragraph | Full Text | PDF (2,829K) | Supplementary information
See also: News and Views by Raimond
Direct observation of the discrete character of intrinsic localized modes in an antiferromagnet p486
M. Sato and A. J. Sievers
doi:10.1038/nature03038
First paragraph | Full Text | PDF (361K)
See also: News and Views by Campbell
Room-temperature fabrication of transparent flexible thin-film transistors using amorphous oxide semiconductors p488
Kenji Nomura, Hiromichi Ohta, Akihiro Takagi, Toshio Kamiya, Masahiro Hirano and Hideo Hosono
doi:10.1038/nature03090
First paragraph | Full Text | PDF (386K)
Equilibrium cluster formation in concentrated protein solutions and colloids p492
Anna Stradner, Helen Sedgwick, Frédéric Cardinaux, Wilson C. K. Poon, Stefan U. Egelhaaf and Peter Schurtenberger
doi:10.1038/nature03109
First paragraph | Full Text | PDF (330K) | Supplementary information
A humid climate state during the Palaeocene/Eocene thermal maximum p495
Gabriel J. Bowen, David J. Beerling, Paul L. Koch, James C. Zachos and Thomas Quattlebaum
doi:10.1038/nature03115
First paragraph | Full Text | PDF (279K) | Supplementary information
Indirect reciprocity can stabilize cooperation without the second-order free rider problem p499
Karthik Panchanathan and Robert Boyd
doi:10.1038/nature02978
First paragraph | Full Text | PDF (211K) | Supplementary information
See also: News and Views by Fehr
Physical performance and darwinian fitness in lizards p502
Jean-François Le Galliard, Jean Clobert and Régis Ferrière
doi:10.1038/nature03057
First paragraph | Full Text | PDF (217K) | Supplementary information
Predator-induced behaviour shifts and natural selection in field-experimental lizard populations p505
Jonathan B. Losos, Thomas W. Schoener and David A. Spiller
doi:10.1038/nature03039
First paragraph | Full Text | PDF (174K) | Supplementary information
Magnetoreception and its trigeminal mediation in the homing pigeon p508
Cordula V. Mora, Michael Davison, J. Martin Wild and Michael M. Walker
doi:10.1038/nature03077
First paragraph | Full Text | PDF (291K) | Supplementary information
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity p512
Marcus Maurer, Jochen Wedemeyer, Martin Metz, Adrian M. Piliponsky, Karsten Weller, Devavani Chatterjea, David E. Clouthier, Masashi M. Yanagisawa, Mindy Tsai and Stephen J. Galli
doi:10.1038/nature03085
First paragraph | Full Text | PDF (442K) | Supplementary information
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II p517
Minkyu Kim, Nevan J. Krogan, Lidia Vasiljeva, Oliver J. Rando, Eduard Nedea, Jack F. Greenblatt and Stephen Buratowski
doi:10.1038/nature03041
First paragraph | Full Text | PDF (458K) | Supplementary information
Human 5' 
3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites p522
Steven West, Natalia Gromak and Nick J. Proudfoot
doi:10.1038/nature03035
First paragraph | Full Text | PDF (241K)
Autocatalytic RNA cleavage in the human -globin pre-mRNA promotes transcription termination p526
Alexandre Teixeira, Abdessamad Tahiri-Alaoui, Steve West, Benjamin Thomas, Aroul Ramadass, Igor Martianov, Mick Dye, William James, Nick J. Proudfoot and Alexandre Akoulitchev
doi:10.1038/nature03032
First paragraph | Full Text | PDF (304K) | Supplementary information
Naturejobs
ProspectsOut of fashion p531
Paul Smaglik
doi:10.1038/nj7016-531a
Careers and Recruitment
Material gains p532
The marriage of engineering, medicine and biology is offering people from a wide range of disciplines the chance to accelerate their careers. Myrna Watanabe investigates a growth industry.
Myrna Watanabe
doi:10.1038/nj7016-532a