Figures and Tables

From the following article:

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

Yentram Huyen, Omar Zgheib, Richard A. DiTullio Jr, Vassilis G. Gorgoulis, Panayotis Zacharatos, Tom J. Petty, Emily A. Sheston, Hestia S. Mellert, Elena S. Stavridi and Thanos D. Halazonetis

Nature 432, 406-411(18 November 2004)

doi:10.1038/nature03114

BACK TO ARTICLE
Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Evolutionary conservation and three-dimensional structure of the human 53BP1 tandem tudor domain.

Full size figure and legend (77K)
Figure 2 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 2

Mapping functionally important 53BP1 residues on the surface of its tandem tudor domain.

Full size figure and legend (30K)
Figure 3 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 3

Binding of 53BP1 tandem tudor domain to histone H3 methylated on Lys 79.

Full size figure and legend (59K)
Figure 4 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 4

Methylation of histone H3 on Lys 79 and changes in higher-order chromatin structure recruit 53BP1 to sites of DSBs and chromatin.

Full size figure and legend (55K)
BACK TO ARTICLE