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News and Views
Nature 432, 157-158 (11 November 2004) | doi:10.1038/432157a; Published online 10 November 2004
DNA repair: Big engine finds small breaks
Anna Marie Pyle1
Abstract
When a break occurs in the DNA double helix, it must be dealt with rapidly. The structure of one of the cellular machines responsible is now revealed, offering insights into its impressive speed and flexibility.
A double-strand break in DNA is the cellular equivalent of a three-alarm fire. As any taxpaying citizen knows, most communities maintain an impressive collection of hardware for dealing with major emergencies.
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