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Editorials

Burning issues p131

The Kyoto Protocol is just a small first step in restricting man's influence on climate. If we can't prevent fires in Indonesia, such international efforts to limit the effects of climate change could be in vain.

doi:10.1038/432131a


The stem-cell state p131

California's citizens have changed the landscape of a key area of biology — with intriguing implications for everyone else.

doi:10.1038/432131b


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News

Watchdogs call academies to account over conflicts of interest p133

Coal-mining committee accused of unhealthy ties to industry.

Tony Reichhardt

doi:10.1038/432133a


Trust gives warm welcome to open access p134

Wellcome Trust endorses public archive for biomedical research.

Jim Giles

doi:10.1038/432134a


Leukaemia sleuths accuse state of nuclear cover-up p134

German cancer commission members resign in protest over 'secret lab'.

Barbara Simm

doi:10.1038/432134b


Joys match fears as California agrees to stem-cell proposal p135

State programme bypasses federal opposition to research.

Jonathan Knight

doi:10.1038/432135a


Bush set to keep core science team for second term p135

US President's line-up of science advisers shapes up.

Emma Marris

doi:10.1038/432135b


Herbicide critic dropped from pollution conference p136

Biologist accuses officials of censorship for cancelling his talk.

Rex Dalton

doi:10.1038/432136a


Hopes rise for RNA therapy as mouse study hits target p136

Safety concerns eased for promising medical technique.

Erika Check

doi:10.1038/432136b


Creative Commons ponders share options p137

Alternative licensing scheme for scientists set to launch.

Paula Gould

doi:10.1038/432137a


WHO seeks system for tracking global clinical trials p137

Groundswell of support seen for easy-access register of medical data.

Erika Check

doi:10.1038/432137b


News in brief p138

doi:10.1038/432138a


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News Features

Zoology: A mole in hand... p142

A strange Australian mole has eluded scientific study for more than a century. Now biologists are teaming up with Aboriginal trackers to unearth the secrets of the itjaritjari. Carina Dennis checks on their progress.

doi:10.1038/432142a


Land remediation: Borneo is burning p144

Vast tracts of Indonesia's peat swamps have been drained in a misguided attempt to turn them into rice plantations. Now the landscape burns every year, belching smoke and hastening global warming. Peter Aldhous investigates.

doi:10.1038/432144a


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Correspondence

Linear models can't keep up with sport gender gap p147

Will women runners ever overtake men at the Olympics? Don't hold your breath.

Weia Reinboud

doi:10.1038/432147a


Sprint research runs into a credibility gap p147

Kenneth Rice

doi:10.1038/432147b


Biology students find holes in gap study p147

Advanced Placement Biology Class

doi:10.1038/432147c


Mind the gap: women racers are falling behind p147

N. C. Craig Sharp

doi:10.1038/432147d


Mind the gap: women racers are falling behind p147

doi:10.1038/432147e


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Books and Arts

The science of life and death p149

A look at the development of biological weapons and the threat they carry.

Malcolm Dando reviews Biological Weapons: From the Invention of State-Sponsored Programs to Contemporary Bioterrorism by Jeanne Guillemin

doi:10.1038/432149a


The view from Budapest p150

Henryk Eisenberg reviews Our Lives: Encounters of a Scientist by István Hargittai

doi:10.1038/432150a


The art of seeing science p151

Stefano Grillo reviews Leonardo by Martin Kemp

doi:10.1038/432151a


Film:  The story of life p151

Federica Castellani

doi:10.1038/432151b


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Essay

Turning points

Making waves p153

How a stroll in the park led to the beginning of quantum electronics.

Charles H. Townes

doi:10.1038/432153a


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News and Views

Medicine:  A cholesterol connection in RNAi p155

RNA interference — RNAi for short — might provide a way to silence disease-associated genes, but problems of delivery have hampered progress. Those problems may have been solved, at least in animal studies.

John J. Rossi

doi:10.1038/432155a


Earth science:  Mantle mapped in the desert p156

How does variation in ocean-floor rocks arise from differences in the temperature of their mantle source? A new angle on the question comes from painstaking work on one of the geological wonders of the world.

Georges Ceuleneer

doi:10.1038/432156a


DNA repair:  Big engine finds small breaks p157

When a break occurs in the DNA double helix, it must be dealt with rapidly. The structure of one of the cellular machines responsible is now revealed, offering insights into its impressive speed and flexibility.

Anna Marie Pyle

doi:10.1038/432157a


Ecology:  Hope in the hills for tundra? p159

Will global warming cause northern forests to spread into arctic tundra? A study of black spruce suggests that the answer is complex and varies according to latitude and altitude.

Peter D. Moore

doi:10.1038/432159a


100 and 50 years ago p160

doi:10.1038/432160a


Animal behaviour:  Rank crime and punishment p160

In paper wasps, facial markings are cheap 'status badges' that would seem to be susceptible to cheating. But wasps punish those whose markings lie. Social competition is, it appears, a strong selective force.

Joan E. Strassmann

doi:10.1038/432160b


Plant development:  A bunch of leaves p161

Christopher Surridge

doi:10.1038/432161a


Condensed-matter physics:  A magnetic pendulum p162

Where two oppositely magnetized regions meet, there is a so-called domain wall. Under the right conditions, this wall can be made to oscillate like a pendulum, suggesting a new approach to electronics.

Claude Chappert and Thibaut Devolder

doi:10.1038/432162a


Research highlights p163

doi:10.1038/432163a


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Brief Communications

Laser beams:  Knotted threads of darkness p165

Dark lines within a laser beam can be manipulated to form stable vortex knots.

Jonathan Leach, Mark R. Dennis, Johannes Courtial and Miles J. Padgett

doi:10.1038/432165a


Plant genetics:  Gene transfer from parasitic to host plants p165

Jeffrey P. Mower, Sas carona Stefanovic acute, Gregory J. Young and Jeffrey D. Palmer

doi:10.1038/432165b


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Brief Communications Arising

Evolution:  How do characters evolve?

Andy Purvis

doi:10.1038/nature03092


Evolution:  How do characters evolve? (reply)

Robert E. Ricklefs

doi:10.1038/nature03093


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Articles

Mantle segmentation along the Oman ophiolite fossil mid-ocean ridge p167

Laurent Le Mée, Jacques Girardeau and Christophe Monnier

doi:10.1038/nature03075

See also: News and Views by Ceuleneer


Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs p173

Jürgen Soutschek, Akin Akinc, Birgit Bramlage, Klaus Charisse, Rainer Constien, Mary Donoghue, Sayda Elbashir, Anke Geick, Philipp Hadwiger, Jens Harborth, Matthias John, Venkitasamy Kesavan, Gary Lavine, Rajendra K. Pandey, Timothy Racie, Kallanthottathil G. Rajeev, Ingo Röhl, Ivanka Toudjarska, Gang Wang, Silvio Wuschko, David Bumcrot, Victor Koteliansky, Stefan Limmer, Muthiah Manoharan and Hans-Peter Vornlocher

doi:10.1038/nature03121

See also: News and Views by Rossi


The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system p179

Xiaowei Lu, Ferdinand le Noble, Li Yuan, Quingjan Jiang, Benjamin de Lafarge, Daisuke Sugiyama, Christiane Bréant, Filip Claes, Frederik De Smet, Jean-Léon Thomas, Monica Autiero, Peter Carmeliet, Marc Tessier-Lavigne and Anne Eichmann

doi:10.1038/nature03080


Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks p187

Martin R. Singleton, Mark S. Dillingham, Martin Gaudier, Stephen C. Kowalczykowski and Dale B. Wigley

doi:10.1038/nature02988

See also: News and Views by Pyle


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Letters to Nature

A characteristic size of approx10 Mpc for the ionized bubbles at the end of cosmic reionization p194

J. Stuart B. Wyithe and Abraham Loeb

doi:10.1038/nature03033


Strong coupling in a single quantum dot–semiconductor microcavity system p197

J. P. Reithmaier, G. Se ogonk, A. Löffler, C. Hofmann, S. Kuhn, S. Reitzenstein, L. V. Keldysh, V. D. Kulakovskii, T. L. Reinecke and A. Forchel

doi:10.1038/nature02969


Vacuum Rabi splitting with a single quantum dot in a photonic crystal nanocavity p200

T. Yoshie, A. Scherer, J. Hendrickson, G. Khitrova, H. M. Gibbs, G. Rupper, C. Ell, O. B. Shchekin and D. G. Deppe

doi:10.1038/nature03119


Current-induced resonance and mass determination of a single magnetic domain wall p203

Eiji Saitoh, Hideki Miyajima, Takehiro Yamaoka and Gen Tatara

doi:10.1038/nature03009

See also: News and Views by Chappert & Devolder


A fast low-power optical memory based on coupled micro-ring lasers p206

Martin T. Hill, Harmen J. S. Dorren, Tjibbe de Vries, Xaveer J. M. Leijtens, Jan Hendrik den Besten, Barry Smalbrugge, Yok-Siang Oei, Hans Binsma, Giok-Djan Khoe and Meint K. Smit

doi:10.1038/nature03045


Prolonged KREEP magmatism on the Moon indicated by the youngest dated lunar igneous rock p209

Lars E. Borg, Charles K. Shearer, Yemane Asmerom and James J. Papike

doi:10.1038/nature03070


Nonindependence of mammalian dental characters p211

Aapo T. Kangas, Alistair R. Evans, Irma Thesleff and Jukka Jernvall

doi:10.1038/nature02927


Disposable-soma senescence mediated by sexual selection in an ungulate p215

Juan Carranza, Susana Alarcos, Cristina B. Sánchez-Prieto, Juliana Valencia and Concha Mateos

doi:10.1038/nature03004


A socially enforced signal of quality in a paper wasp p218

Elizabeth A. Tibbetts and James Dale

doi:10.1038/nature02949

See also: News and Views by Strassmann


Environmental biosafety and transgenic potato in a centre of diversity for this crop p222

Carolina Celis, Maria Scurrah, Sue Cowgill, Susana Chumbiauca, Jayne Green, Javier Franco, Gladys Main, Daan Kiezebrink, Richard G. F. Visser and Howard J. Atkinson

doi:10.1038/nature03048


A pancreatic islet-specific microRNA regulates insulin secretion p226

Matthew N. Poy, Lena Eliasson, Jan Krutzfeldt, Satoru Kuwajima, Xiaosong Ma, Patrick E. MacDonald, Sébastien Pfeffer, Thomas Tuschl, Nikolaus Rajewsky, Patrik Rorsman and Markus Stoffel

doi:10.1038/nature03076


Processing of primary microRNAs by the Microprocessor complex p231

Ahmet M. Denli, Bastiaan B. J. Tops, Ronald H. A. Plasterk, René F. Ketting and Gregory J. Hannon

doi:10.1038/nature03049


The Microprocessor complex mediates the genesis of microRNAs p235

Richard I. Gregory, Kai-ping Yan, Govindasamy Amuthan, Thimmaiah Chendrimada, Behzad Doratotaj, Neil Cooch and Ramin Shiekhattar

doi:10.1038/nature03120


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Technology Features

Cell signalling:  Making connections p243

Technological innovations in detecting and studying protein–protein interactions are providing new ways of doing research in cell signalling. Diane Gershon investigates.

Diane Gershon

doi:10.1038/432243a


In the market-place p243

doi:10.1038/432243b


Quantum dots show their true colours p247

doi:10.1038/432247a


Probing real-time protein interactions p249

doi:10.1038/432249a


Table of suppliers p250

doi:10.1038/432250a


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Naturejobs

Prospects

The secrets of success p253

Paul Smaglik

doi:10.1038/nj7014-253a


Special Report

Getting on the fast-track to full-time employment p254

The road to your first full-time position can be long and tortuous. But some researchers have found a shortcut to success. Eugene Russo reports.

Eugene Russo

doi:10.1038/nj7014-254a


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