Figures and Tables

From the following article:

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

Tsan Xiao, Junichi Takagi, Barry S. Coller, Jia-Huai Wang and Timothy A. Springer

Nature 432, 59-67(4 November 2004)

doi:10.1038/nature02976

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Quaternary rearrangements in the integrin ectodomain.

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Figure 2

Structure of the alphaIIbbeta3 headpiece.

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Figure 3

The binding sites for ligand-mimetic antagonists and fibrinogen at the alpha/beta subunit interface.

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Figure 4

Allostery in the beta I domain and comparison with alpha I domain.

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Figure 5

The hybrid and PSI domains and their interfaces.

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