Table of contents
Volume 431 Number 7012 pp1023-1128
Editorials
Struggling with the flu p1023
The shortages of flu vaccine in the United States this autumn have laid bare some troubling weaknesses in the nation's public-health system.
doi:10.1038/4311023a
Fishing for excuses p1023
The message from researchers about the state of European fish stocks is consistent, but its delivery could be improved.
doi:10.1038/4311023b
News
Science shares the limelight as election battle enters final phase p1025
US presidential candidates cover everything from nuclear waste to the flu vaccine.
Erika Check and Geoff Brumfiel
doi:10.1038/4311025a
Ultrasound scans accused of disrupting brain development p1026
$3 million study to test effects of scans on monkeys.
Jim Giles
doi:10.1038/4311026a
Geneticists struggle towards consensus on place for 'race' p1026
Meeting will look at importance of ethnicity in medical research.
Meredith Wadman
doi:10.1038/4311026b
Comet impact theory faces repeat analysis p1027
Study starts to investigate cause of mass extinction 250 million years ago.
Rex Dalton
doi:10.1038/4311027a
Spain's budget fails basic science, researchers charge p1027
New government accused of breaking funding promises.
Monica Salamone
doi:10.1038/4311027b
Deluge of typhoons may aid forecast models p1028
Japan's 'super-abnormal' storms bring buckets of data.
David Cyranoski
doi:10.1038/4311028a
Generic drugs allowed in global trial of AIDS therapy p1028
US National Institutes of Health accepts generics into giant drug trial.
Erika Check
doi:10.1038/4311028b
Little lady of Flores forces rethink of human evolution p1029
Rex Dalton
doi:10.1038/4311029a
Novartis goes public with DNA data in bid to tackle diabetes p1029
Private-public partnership should help hunt for disease genes.
Jonathan Knight
doi:10.1038/4311029b
News Features
Earthquake prediction: A seismic shift in thinking p1032
Earthquake researchers in the United States have long shunned the word 'prediction'. But, thanks to improved data and a change in public perception, cracks are beginning to appear in their resolve. David Cyranoski tracks the debate.
doi:10.1038/4311032a
Astronomy: Bagging bursts, swiftly p1035
The gamma rays spat out by dying stars last an instant. Tony Reichhardt reports on the fast-response satellite that hopes to capture them.
doi:10.1038/4311035a
Correspondence
Scientists must conquer reluctance to speak out p1036
When science is under political assault, keeping a dignified silence is counterproductive.
Stephen Porder, Kai M. A. Chan and Paul A. T. Higgins
doi:10.1038/4311036a
Why leave it to others to speak up about science? p1036
Ian Flintoff
doi:10.1038/4311036b
Knowledge is a good base to campaign from p1036
Kaihsu Tai
doi:10.1038/4311036c
Books and Arts
Driven to diffraction p1037
How Lawrence Bragg and his father used X-rays to solve crystal structures.
Kenneth C. Holmes reviews Light is a Messenger: the Life and Science of William Lawrence Bragg by Graeme K. Hunter
doi:10.1038/4311037a
Shaking up seismology p1038
Naomi Oreskes reviews The Big One: The Earthquake That Rocked Early America and Helped Create a Science by Jake Page and Charles Officer
doi:10.1038/4311038a
Science in Culture
Betty Beaumont's Ocean Landmark is in deep water. p1039
From art to environment
Martin Kemp reviews
doi:10.1038/4311039a
Population biology on the wing p1040
Norman Myers reviews On the Wings of Checkerspots: A Model System for Population Biology
doi:10.1038/4311040a
Correction p1040
doi:10.1038/4311040b
Essay
Turning pointsA wake-up call p1041
How failing a PhD led to a strategy for a successful scientific career.
Bruce Alberts
doi:10.1038/4311041a
News and Views
Palaeoanthropology: Human evolution writ small p1043
We are the only living species of the genus Homo. Given the startling results of a cave excavation in Southeast Asia, it seems that we coexisted with another species until much more recently than had been thought.
Marta Mirazón Lahr and Robert Foley
doi:10.1038/4311043a
Astronomy: Tycho's mystery companion p1044
A famous sixteenth-century supernova, seen by Tycho Brahe, is still a hot topic. The stellar explosion might have been initiated by a companion star — and modern astronomers have at last identified it.
David Branch
doi:10.1038/4311044a
100 and 50 years ago p1045
doi:10.1038/4311045a
Conservation biology: Biodiversity barometers p1046
The Red List Index is a new indicator of species' extinction risk. It will make a major contribution in measuring the success of an internationally agreed aim to slow biodiversity loss by 2010.
Thomas Brooks and Elizabeth Kennedy
doi:10.1038/4311046a
Solar physics: Spots from rings p1047
An ingeniously constructed record of sunspot activity shows that the current episode is the most intense for several thousand years. But that does not let us off the anthropogenic hook of global warming.
Paula J. Reimer
doi:10.1038/4311047a
Molecular motors: Smooth coupling in Salmonella p1047
Christopher Surridge
doi:10.1038/4311047b
Evolutionary biology: Mortality and lifespan p1048
How does natural selection affect lifespan? The question has exercised biologists for some years. The latest twist comes from ingenious experiments on tropical fish from different ecological backgrounds.
Peter A. Abrams
doi:10.1038/4311048a
Correction p1049
doi:10.1038/4311049a
Brief Communications
Phylogeography: English elm is a 2,000-year-old Roman clone p1053
This tree's genetic uniformity may have helped to fell entire European populations.
Luis Gil, Pablo Fuentes-Utrilla, Álvaro Soto, M. Teresa Cervera and Carmen Collada
doi:10.1038/4311053a
First paragraph | Full Text | PDF (202K) | Supplementary information
Articles
A new small-bodied hominin from the Late Pleistocene of Flores, Indonesia p1055
P. Brown, T. Sutikna, M. J. Morwood, R. P. Soejono, Jatmiko, E. Wayhu Saptomo and Rokus Awe Due
doi:10.1038/nature02999
Abstract | Full Text | PDF (361K) | Supplementary information
See also: News and Views by Mirazón Lahr & Foley
Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism p1062
Fadel A. Samatey, Hideyuki Matsunami, Katsumi Imada, Shigehiro Nagashima, Tanvir R. Shaikh, Dennis R. Thomas, James Z. Chen, David J. DeRosier, Akio Kitao and Keiichi Namba
doi:10.1038/nature02997
Abstract | Full Text | PDF (655K) | Supplementary information
Letters to Nature
The binary progenitor of Tycho Brahe's 1572 supernova p1069
Pilar Ruiz-Lapuente, Fernando Comeron, Javier Méndez, Ramon Canal, Stephen J. Smartt, Alexei V. Filippenko, Robert L. Kurucz, Ryan Chornock, Ryan J. Foley, Vallery Stanishev and Rodrigo Ibata
doi:10.1038/nature03006
First paragraph | Full Text | PDF (260K) | Supplementary information
See also: News and Views by Branch
Recent ice-rich deposits formed at high latitudes on Mars by sublimation of unstable equatorial ice during low obliquity p1072
Benjamin Levrard, François Forget, Franck Montmessin and Jacques Laskar
doi:10.1038/nature03055
First paragraph | Full Text | PDF (374K)
Continuous generation of single photons with controlled waveform in an ion-trap cavity system p1075
Matthias Keller, Birgit Lange, Kazuhiro Hayasaka, Wolfgang Lange and Herbert Walther
doi:10.1038/nature02961
First paragraph | Full Text | PDF (584K) | Supplementary information
Crystallization of charge holes in the spin ladder of Sr14Cu24O41 p1078
P. Abbamonte, G. Blumberg, A. Rusydi, A. Gozar, P. G. Evans, T. Siegrist, L. Venema, H. Eisaki, E. D. Isaacs and G. A. Sawatzky
doi:10.1038/nature02925
First paragraph | Full Text | PDF (305K)
All-optical control of light on a silicon chip p1081
Vilson R. Almeida, Carlos A. Barrios, Roberto R. Panepucci and Michal Lipson
doi:10.1038/nature02921
First paragraph | Full Text | PDF (399K)
Unusual activity of the Sun during recent decades compared to the previous 11,000 years p1084
S. K. Solanki, I. G. Usoskin, B. Kromer, M. Schüssler and J. Beer
doi:10.1038/nature02995
First paragraph | Full Text | PDF (261K) | Supplementary information
See also: News and Views by Reimer
Archaeology and age of a new hominin from Flores in eastern Indonesia p1087
M. J. Morwood, R. P. Soejono, R. G. Roberts, T. Sutikna, C. S. M. Turney, K. E. Westaway, W. J. Rink, J.- x. Zhao, G. D. van den Bergh, Rokus Awe Due, D. R. Hobbs, M. W. Moore, M. I. Bird and L. K. Fifield
doi:10.1038/nature02956
First paragraph | Full Text | PDF (355K) | Supplementary information
See also: News and Views by Mirazón Lahr & Foley
Bioturbators enhance ecosystem function through complex biogeochemical interactions p1092
Andrew M. Lohrer, Simon F. Thrush and Max M. Gibbs
doi:10.1038/nature03042
First paragraph | Full Text | PDF (366K) | Supplementary information
Effect of extrinsic mortality on the evolution of senescence in guppies p1095
David N. Reznick, Michael J. Bryant, Derek Roff, Cameron K. Ghalambor and Dionna E. Ghalambor
doi:10.1038/nature02936
First paragraph | Full Text | PDF (402K) | Supplementary information
See also: News and Views by Abrams
Population density drives the local evolution of a threshold dimorphism p1099
Joseph L. Tomkins and Gordon S. Brown
doi:10.1038/nature02918
First paragraph | Full Text | PDF (1,151K) | Supplementary information
Non-mitochondrial complex I proteins in a hydrogenosomal oxidoreductase complex p1103
Sabrina D. Dyall, Weihong Yan, Maria G. Delgadillo-Correa, Adam Lunceford, Joseph A. Loo, Catherine F. Clarke and Patricia J. Johnson
doi:10.1038/nature02990
First paragraph | Full Text | PDF (930K) | Supplementary information
The genome of Cryptosporidium hominis p1107
Ping Xu, Giovanni Widmer, Yingping Wang, Luiz S. Ozaki, Joao M. Alves, Myrna G. Serrano, Daniela Puiu, Patricio Manque, Donna Akiyoshi, Aaron J. Mackey, William R. Pearson, Paul H. Dear, Alan T. Bankier, Darrell L. Peterson, Mitchell S. Abrahamsen, Vivek Kapur, Saul Tzipori and Gregory A. Buck
doi:10.1038/nature02977
First paragraph | Full Text | PDF (563K) | Supplementary information
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer p1112
Catherine M. Shachaf, Andrew M. Kopelman, Constadina Arvanitis, Åsa Karlsson, Shelly Beer, Stefanie Mandl, Michael H. Bachmann, Alexander D. Borowsky, Boris Ruebner, Robert D. Cardiff, Qiwei Yang, J. Michael Bishop, Christopher H. Contag and Dean W. Felsher
doi:10.1038/nature03043
First paragraph | Full Text | PDF (553K) | Supplementary information
Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control p1118
Satoru Mimura, Takashi Seki, Seiji Tanaka and John F. X. Diffley
doi:10.1038/nature03024
First paragraph | Full Text | PDF (572K) | Supplementary information
corrigendum: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects p1123
Toshimasa Yamauchi, Junji Kamon, Yusuke Ito, Atsushi Tsuchida, Takehiko Yokomizo, Shunbun Kita, Takuya Sugiyama, Makoto Miyagishi, Kazuo Hara, Masaki Tsunoda, Koji Murakami, Toshiaki Ohteki, Shoko Uchida, Sato Takekawa, Hironori Waki, Nelson H. Tsuno, Yoichi Shibata, Yasuo Terauchi, Philippe Froguel, Kazuyuki Tobe, Shigeo Koyasu, Kazunari Taira, Toshio Kitamura, Takao Shimizu, Ryozo Nagai and Takashi Kadowaki
doi:10.1038/nature03091
Full Text | PDF (67K) | Supplementary information
Naturejobs
ProspectsMaking the match p1125
Paul Smaglik
doi:10.1038/nj7012-1125a
Special Report
Fast Track: charting the course of your postdoc p1126
Are you on course for the career you want? Don't follow the crowd and lose your direction, warns Eugene Russo. Instead, map out your own postdoc path.
Eugene Russo
doi:10.1038/nj7012-1126a
Career View
Graduate Journal: PhD limitations p1128
Philipp Angerer
doi:10.1038/nj7012-1128a
Recruiters & Industry p1128
Grace Wong
doi:10.1038/nj7012-1128b
Movers p1128
doi:10.1038/nj7012-1128c