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From the following article:

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

Catherine M. Shachaf, Andrew M. Kopelman, Constadina Arvanitis, Åsa Karlsson, Shelly Beer, Stefanie Mandl, Michael H. Bachmann, Alexander D. Borowsky, Boris Ruebner, Robert D. Cardiff, Qiwei Yang, J. Michael Bishop, Christopher H. Contag and Dean W. Felsher

Nature 431, 1112-1117(28 October 2004)

doi:10.1038/nature03043

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Conditional MYC overexpression in the liver induces hepatocellular cancer whereas MYC inactivation results in sustained tumour regression.

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Figure 2

MYC inactivation in liver tumours results in rapid tumour regression associated with loss of expression of tumour markers, differentiation and apoptosis.

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Figure 3

MYC inactivation in liver tumours results in the formation of normal hepatic structures.

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Figure 4

Tumour dormancy observed in liver tumours after MYC inactivation.

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