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News and Views
Nature 431, 747-748 (14 October 2004) | doi:10.1038/431747a; Published online 13 October 2004
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Neurodegenerative disease: Neuron protection agency
Harry T. Orr1
Abstract
The results of an innovative way of tracing the life and death of neurons in culture favour one side of a debate about the protein accumulations associated with certain disorders of the nervous system.
On page 805 of this issue, Arrasate and colleagues1 show that clumps of mutant protein, seen in certain neurons and characteristic of Huntington's disease, reduce the chance that the neurons will die — at least in culture. So, why is this worth noting?
- Harry T. Orr is at the Institute of Human Genetics, University of Minnesota, 516 Delaware St SE, Minneapolis, Minnesota 55455-0374, USA.
e-mail: Email: harry@lenti.med.umn.edu
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