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Cell biology

Sight at the end of the tunnel

Nature volume 431, pages 520–522 (2004)Cite this article

A chaperone molecule called trigger factor binds new polypeptide chains as they emerge from the protein-synthesis machinery. Crystal structures suggest that this molecule forms a hydrophobic ‘cradle’.

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Figure 1: Chaperones at the ribosome.

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Authors and Affiliations

  1. Department of Genetics and the Howard Hughes Medical Institute, Boyer Center, Yale School of Medicine, New Haven, 06510, Connecticut, USA

    Arthur Horwich

  2. The Scripps Research Institute, La Jolla, California, USA

    Arthur Horwich

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  1. Arthur Horwich
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Horwich, A. Sight at the end of the tunnel. Nature 431, 520–522 (2004). https://doi.org/10.1038/431520a

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