Editorials

Experiments in publishing p111

Nature's web forum on access to the primary literature has highlighted the risks, as well as the attractions, in enforcing availability without charge to readers.

doi:10.1038/431111a

Full Text | PDF (67K)

Helping depressed children p111

The FDA should improve public information and work to create a publicly accessible clinical-trials database.

doi:10.1038/431111b

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News

Reviewers caution NASA over plans for nuclear-powered craft p113

Projects may be too expensive to fly

Tony Reichhardt

doi:10.1038/431113a

Full Text | PDF (291K)

Peer-reviewed paper defends theory of intelligent design p114

Critics of evolution score publishing success

Jim Giles

doi:10.1038/431114a

Full Text | PDF (218K)

Conservers plead for funds to protect Europe's heritage p114

Money to preserve historic objects in decline

Alison Abbott

doi:10.1038/431114b

Full Text | PDF (218K)

Biomedical agency floats open-access plan p115

National Institutes of Health to publish papers online

Geoff Brumfiel

doi:10.1038/431115a

Full Text | PDF (152K)

Ocean fix for climate change finds tentative support p115

Marine life steers clear of waters poisoned with carbon dioxide

Jim Giles

doi:10.1038/431115b

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Suppliers step in to manage chemical use p116

Companies make more money by making less waste

Jim Giles

doi:10.1038/431116a

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China increases share of global scientific publications p116

Big country sees big science boom

David Cyranoski

doi:10.1038/431116b

Full Text | PDF (199K)

US chemist attacks consumer magazine's food safety work p117

Consumer Reports 'ignored' research, says scientist

Jim Giles

doi:10.1038/431117a

Full Text | PDF (286K)

Only pride hurt as predicted quake fails to strike California p117

Forecast failure for controversial researcher

David Cyranoski

doi:10.1038/431117b

Full Text | PDF (286K)

News in brief p118

doi:10.1038/431118a

Full Text | PDF (67K)

News Features

Lightning research: The bolt catchers p120

Every summer, Florida plays host to researchers who fire rockets at the sky to create lightning. And having captured the bolts, the group has found something shocking, as Mark Schrope finds out.

doi:10.1038/431120a

Full Text | PDF (589K)

Antidepressants: Bitter pills p122

They were hailed as wonder drugs to banish depression, but may cause suicidal thoughts in some children. Companies are under attack for failing to publish these data. Erika Check considers the science behind a scandal.

doi:10.1038/431122a

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Correspondence

Science priorities ignore Colombia's water needs p125

The government did not consult with the scientific community on reforms.

Germán Poveda

doi:10.1038/431125a

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Complexity of the body calls for animal research p125

Charles G. Smith

doi:10.1038/431125b

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Classroom volunteers inspire young ecologists p125

Sarah Abramson

doi:10.1038/431125c

Full Text | PDF (70K)

Books and Arts

Symbol minded p127

Relationships with others have helped to shape our ability to learn language.

Peter Hobson reviews The First Idea: How Symbols, Language, and Intelligence Evolved From Our Primate Ancestors to Modern Humans by Stanley I. Greenspan and Stuart G. Shanker

doi:10.1038/431127a

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Sizing up a growing field p128

Brendan D. Manning and Lewis C. Cantley review Cell Growth: Control of Cell Size

doi:10.1038/431128a

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New and revised textbooks p128

doi:10.1038/431128b

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Science in culture p129

Werner Tübke's huge wall-painting will grace a new building at the University of Leipzig.

Alison Abbott

doi:10.1038/431129a

Full Text | PDF (349K)

Essay

Natural proportions p131

Redfield ratios: the uniformity of elemental ratios in the oceans and the life they contain underpins our understanding of marine biogeochemistry.

Paul G. Falkowski and Cabell S. Davis

doi:10.1038/431131a

Full Text | PDF (147K)

News and Views

Palaeoclimate:  Into an ice age p133

Analyses of a new ice core from Greenland yield the first high-resolution picture of the start of the last ice age in the Northern Hemisphere, and of the onset of climate instability as our planet cooled.

Kurt M. Cuffey

doi:10.1038/431133a

Full Text | PDF (165K)

Evolutionary biology:  Early evolution comes full circle p134

Biologists use phylogenetic trees to depict the history of life. But according to a new and roundabout view, such trees are not the best way to summarize life's deepest evolutionary relationships.

William Martin and T. Martin Embley

doi:10.1038/431134a

Full Text | PDF (315K)

Neurobiology:  Feeding the brain p137

In computationally active areas of the brain, the blood flow is increased to provide more energy to nerve cells. New data fuel the controversy over how this energy supply is regulated.

Claire Peppiatt and David Attwell

doi:10.1038/431137a

Full Text | PDF (169K)

Condensed-matter physics:  The qubit and the cavity p138

Coherent coupling of superconducting qubits and electromagnetic modes, analogous to atom–photon coupling, has been demonstrated — a step towards the communication of quantum information.

Yu. Makhlin, G. Schön and A. Shnirman

doi:10.1038/431138a

Full Text | PDF (158K)

Animal behaviour:  Relative size in the mating game p139

A common trend in size differences between males and females is a long-standing puzzle. A study of shorebirds shows that the type and strength of competition for mates may explain much of the pattern.

Malte Andersson and Johan Wallander

doi:10.1038/431139a

Full Text | PDF (288K)

100 and 50 years ago p139

doi:10.1038/431139b

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Cell biology:  An unexpected social servant p142

Cells communicate through signals that must be propagated from cell surface to nucleus. Tracking the signals generated by the transforming growth factor- protein reveals a surprising partner in this process.

Christine Le Roy and Jeffrey L. Wrana

doi:10.1038/431142a

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Obituary:  Edward B. Lewis (1918–2004) p143

Matthew P. Scott and Peter A. Lawrence

doi:10.1038/431143a

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Research highlights p144

doi:10.1038/431144a

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Brief Communications

Palaeontology:  Parental care in an ornithischian dinosaur p145

A dramatic fossil may shed light on how modern archosaurs became devoted parents.

Qingjin Meng, Jinyuan Liu, David J. Varricchio, Timothy Huang and Chunling Gao

doi:10.1038/431145a

First paragraph | Full Text | PDF (480K)

Bird song:  Superfast muscles control dove's trill p146

Coen P. H. Elemans, Igor L. Y. Spierts, Ulrike K. Müller, Johan L. van Leeuwen and Franz Goller

doi:10.1038/431146a

First paragraph | Full Text | PDF (131K) | Supplementary information

Articles

High-resolution record of Northern Hemisphere climate extending into the last interglacial period p147

North Greenland Ice Core Project members

doi:10.1038/nature02805

Abstract | Full Text | PDF (325K) | Supplementary information

See also: News and Views by Cuffey

The ring of life provides evidence for a genome fusion origin of eukaryotes p152

Maria C. Rivera and James A. Lake

doi:10.1038/nature02848

Abstract | Full Text | PDF (155K) | Supplementary information

See also: News and Views by Martin & Embley

Letters to Nature

Implications for hydrologic processes on Mars from extensive bedrock outcrops throughout Terra Meridiani p156

Brian M. Hynek

doi:10.1038/nature02902

First paragraph | Full Text | PDF (356K)

Coherent dynamics of a flux qubit coupled to a harmonic oscillator p159

I. Chiorescu, P. Bertet, K. Semba, Y. Nakamura, C. J. P. M. Harmans and J. E. Mooij

doi:10.1038/nature02831

First paragraph | Full Text | PDF (297K)

See also: News and Views by Makhlin et al.

Strong coupling of a single photon to a superconducting qubit using circuit quantum electrodynamics p162

A. Wallraff, D. I. Schuster, A. Blais, L. Frunzio, R.- S. Huang, J. Majer, S. Kumar, S. M. Girvin and R. J. Schoelkopf

doi:10.1038/nature02851

First paragraph | Full Text | PDF (1,109K)

Generation of ultraviolet entangled photons in a semiconductor p167

Keiichi Edamatsu, Goro Oohata, Ryosuke Shimizu and Tadashi Itoh

doi:10.1038/nature02838

First paragraph | Full Text | PDF (310K)

A high-performance cathode for the next generation of solid-oxide fuel cells p170

Zongping Shao and Sossina M. Haile

doi:10.1038/nature02863

First paragraph | Full Text | PDF (273K) | Supplementary information

The transition to a sulphidic ocean 1.84 billion years ago p173

Simon W. Poulton, Philip W. Fralick and Donald E. Canfield

doi:10.1038/nature02912

First paragraph | Full Text | PDF (332K) | Supplementary information

Genetic variation increases during biological invasion by a Cuban lizard p177

Jason J. Kolbe, Richard E. Glor, Lourdes Rodríguez Schettino, Ada Chamizo Lara, Allan Larson and Jonathan B. Losos

doi:10.1038/nature02807

First paragraph | Full Text | PDF (331K) | Supplementary information

Ecosystem stability and compensatory effects in the Inner Mongolia grassland p181

Yongfei Bai, Xingguo Han, Jianguo Wu, Zuozhong Chen and Linghao Li

doi:10.1038/nature02850

First paragraph | Full Text | PDF (277K) | Supplementary information

Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits p184

Heather L. True, Ilana Berlin and Susan L. Lindquist

doi:10.1038/nature02885

First paragraph | Full Text | PDF (228K) | Supplementary information

Recollection-like memory retrieval in rats is dependent on the hippocampus p188

Norbert J. Fortin, Sean P. Wright and Howard Eichenbaum

doi:10.1038/nature02853

First paragraph | Full Text | PDF (990K) | Supplementary information

Restricted growth of Schwann cells lacking Cajal bands slows conduction in myelinated nerves p191

Felipe A. Court, Diane L. Sherman, Thomas Pratt, Emer M. Garry, Richard R. Ribchester, David F. Cottrell, Susan M. Fleetwood-Walker and Peter J. Brophy

doi:10.1038/nature02841

First paragraph | Full Text | PDF (407K) | Supplementary information

Calcium transients in astrocyte endfeet cause cerebrovascular constrictions p195

Sean J. Mulligan and Brian A. MacVicar

doi:10.1038/nature02827

First paragraph | Full Text | PDF (397K) | Supplementary information

See also: News and Views by Peppiatt & Attwell

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity p200

Sung Hee Um, Francesca Frigerio, Mitsuhiro Watanabe, Frédéric Picard, Manel Joaquin, Melanie Sticker, Stefano Fumagalli, Peter R. Allegrini, Sara C. Kozma, Johan Auwerx and George Thomas

doi:10.1038/nature02866

First paragraph | Full Text | PDF (850K) | Supplementary information

Cytoplasmic PML function in TGF- signalling p205

Hui-Kuan Lin, Stephan Bergmann and Pier Paolo Pandolfi

doi:10.1038/nature02783

First paragraph | Full Text | PDF (599K) | Supplementary information

See also: News and Views by Roy & Wrana

Induction of DNA methylation and gene silencing by short interfering RNAs in human cells p211

Hiroaki Kawasaki and Kazunari Taira

doi:10.1038/nature02889

First paragraph | Full Text | PDF (792K) | Supplementary information

Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase p217

Gerald W. Hsu, Matthias Ober, Thomas Carell and Lorena S. Beese

doi:10.1038/nature02908

First paragraph | Full Text | PDF (332K) | Supplementary information

Structure of the ESCRT-II endosomal trafficking complex p221

Aitor Hierro, Ji Sun, Alexander S. Rusnak, Jaewon Kim, Gali Prag, Scott D. Emr and James H. Hurley

doi:10.1038/nature02914

First paragraph | Full Text | PDF (298K) | Supplementary information

Naturejobs

The joy of the lab p227

Paul Smaglik

doi:10.1038/nj7005-227a

Full Text | PDF (129K)

Graduate Journal:  Try, try again p228

Sidney Omelon

doi:10.1038/nj7005-228a

Full Text | PDF (82K)

Nuts & Bolts p228

Deb Koen

doi:10.1038/nj7005-228b

Full Text | PDF (82K)

Movers p228

doi:10.1038/nj7005-228c

Full Text | PDF (82K)