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News and Views
Nature 430, 977-979 (26 August 2004) | doi:10.1038/430977a; Published online 25 August 2004
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Head, Protein Production Unit
- The Novo Nordisk Foundation Center for Protein Research
- Copenhagen 2200 Denmark
Director
- The National Center for Complementary and Alternative Medicine (NCCAM)
- Bethesda, MD
Transmissible spongiform encephalopathies: Prion proof in progress
Herman K. Edskes1 & Reed B. Wickner1
Abstract
Whether a protein can transmit disease in mammals has been an open question for some time. The latest test of this idea provides some strong evidence in favour, but is unlikely to end the debate.
Studies of the infectious agent responsible for the transmissible spongiform encephalopathies have spanned more than six decades. But the slow course of these diseases, and experimental difficulties in their study, has left the nature of this agent in doubt.
- Herman K. Edskes and Reed B. Wickner are in the Laboratory of Biochemistry and Genetics, National Institutes of Health, 8 Center Drive, MSC 0830, Bethesda, Maryland 20892-0830, USA.
e-mail: Email: wickner@helix.nih.gov
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