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Nature 430, 942-943 (19 August 2004) | doi:10.1038/430942a; Published online 18 August 2004

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Malaria Winning the drugs war

Robert Ridley1 & Yeya Toure2

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We have the science to make new antimalarials, say Robert Ridley and Yeya Toure, but we need better mechanisms and resources to develop drugs and deliver them.

In the 1990s, prospects for antimalarial chemotherapy became increasingly bleak owing to growing parasite resistance to chloroquine and sulphadoxine-pyrimethamine. Artemisinin-based drugs showed great promise in southeast Asia, but were barely used in Africa because of their cost and a lack of clinical data.

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