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Nature 430, 838-839 (19 August 2004) | doi:10.1038/430838a; Published online 18 August 2004
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Medicinal chemistry: A worthy adversary for malaria
Paul M. O'Neill1
Abstract
A remarkable set of antimalarial drug candidates has been developed by an international collaboration of scientists, using the age-old Chinese herbal medicine artemisinin as a template.
Nearly two billion people live in areas where malaria is endemic, and the incidence of this disease is increasing dramatically, mainly because many malaria-parasite strains have become resistant to the available drugs1. The devastating spread of parasite resistance has prompted the worldwide search for new classes of effective antimalarial drugs.
- Paul M. O'Neill is in the Departments of Chemistry and of Pharmacology, University of Liverpool, Liverpool L69 7ZD, UK.
Email: p.m.oneill01@liverpool.ac.uk
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