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Editorials

On the campaign trail p593

The use and abuse of science is emerging as an issue in the US presidential election. Researchers should seize an opportunity to make their voices heard, whatever their political persuasion.

doi:10.1038/430593a


Weak at the centre p593

Germany's obsessive federalism has become an anachronism that is holding back the nation's science.

doi:10.1038/430593b


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News

Nobel laureates spearhead effort to put Kerry in the White House p595

Researchers hit the campaign trail for the US presidential election

Geoff Brumfiel and Emma Marris

doi:10.1038/430595a


Lab closure sparks fears that US prion research is waning p596

Scientists call for renewed effort in studying proteins that cause brain disease

Helen Pearson

doi:10.1038/430596a


Reform of land use urged as floodwaters rise across Asia p596

Heavy rains and land mismanagement have led to deadly floods

David Cyranoski

doi:10.1038/430596b


From DNA to consciousness — Crick's legacy p597

Francis Crick passes away at the age of 88

Jonathan Knight

doi:10.1038/430597a


'Militant' animal activists trigger British law change p597

UK makes it illegal to gather outside homes or harass lab employees

Jim Giles

doi:10.1038/430597b


Review of tenure refusal uncovers conflicts of interest p598

Ignacio Chapela gets good news on his appeal

Rex Dalton

doi:10.1038/430598a


Biotech funding deal judged to be 'a mistake' for Berkeley p598

Universities should avoid large-scale partnerships with industry, says report

Rex Dalton

doi:10.1038/430598b


Court ruling upsets hopes for career reforms p599

Scheme for young German researchers ruled unconstitutional

Alison Abbott

doi:10.1038/430599a


Size matters when it comes to safety, report warns p599

Royal Society recommends precautionary approach to nanotechnology

Jim Giles

doi:10.1038/430599b


News in brief p600

doi:10.1038/430600a


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News Features

Athens Olympics special: To the edge... and over p602

Special report on the Olympics

doi:10.1038/430602a


A breed apart p603

Olympic athletes are on the edge of normal physiology, finds Alison Abbott.

doi:10.1038/430603a


The medals and the damage done p604

Athletes' punishing schedules push their bodies to the limit. But what happens if they go too far? Jim Giles finds out.

doi:10.1038/430604a


Heart-stopping action p606

Some athletes diagnosed with a genetic heart condition are banned from competitive sport. Laura Spinney discovers how they are fighting for the right to run the risk of death.

doi:10.1038/430606a


Gasping for victory p608

This year's Olympics will take place in Athens, a city renowned for its hot, humid summers and stifling air pollution. Martin Leeb discovers how the athletes plan to overcome the hurdle of these tough conditions.

doi:10.1038/430608a


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Correspondence

Traumatic events take their toll on mental health p611

Results of violence and natural disasters could overwhelm services in developing world.

Menachem Ben-Ezra

doi:10.1038/430611a


OvaCheck: let's not dismiss the concept p611

Josep Villanueva and Paul Tempst

doi:10.1038/430611b


OvaCheck: doubts voiced soon after publication p611

Eleftherios P. Diamandis

doi:10.1038/430611c


Editing for posterity gets red card in Real world p611

Derek Partridge

doi:10.1038/430611d


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Books and Arts

Sex under pressure p613

If sex is so important for evolution, why don't we have more of it?

Robert Foley reviews Why We Do It: Rethinking Sex and the Selfish Gene by Niles Eldredge

doi:10.1038/430613a


The birth of modern science? p614

Mott Greene reviews The Forgotten Revolution: How Science Was Born in 300BC and Why It Had To Be Reborn by Lucio Russo

doi:10.1038/430614a


Into the unknown p615

Diana Kormos Buchwald reviews The Invisible Century: Einstein, Freud, and the Search for Hidden Universes by Richard Panek

doi:10.1038/430615a


Science in culture p616

Geometry lies at the heart of sculptures from the Temple of Zeus.

Stefano Grillo reviews

doi:10.1038/430616a


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Essay

Turning points

The pleasure of learning p617

How an Italian visitor rekindled the joy of science in a war veteran.

Leon Lederman

doi:10.1038/430617a


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News and Views

Palaeontology:  Inside the oldest bird brain p619

Did Archaeopteryx, the most primitive known bird, have 'the right stuff'? Looking into its skull with advanced technology provides insight into the dinosaurian transition to birds, and the evolution of flight.

Lawrence M. Witmer

doi:10.1038/430619a


Semiconductor physics:  The value of seeing nothing p620

Adding atoms to a semiconductor can improve its electronic properties. In an oxide, taking atoms away can have a similar electronic effect — one that could, it seems, be exploited in device applications.

Jochen Mannhart and Darrell G. Schlom

doi:10.1038/430620a


Fisheries science:  Why mothers matter p621

Fish population growth depends on older mothers, which in some species produce more and 'better' offspring than younger fish. When fisheries remove the most productive females, the whole population suffers.

Stephen R. Palumbi

doi:10.1038/430621a


Astronomy:  A faint population of bursts? p623

An unusual gamma-ray burst has been detected, much less energetic than expected. But its similarity to an earlier anomalous event suggests that lower-energy bursts might be more plentiful than had been thought.

Stan Woosley

doi:10.1038/430623a


Ultrafast physics:  Quantum control with a twist p624

Laser pulses can be generated such that their shape and state of polarization change on the scale of a few femtoseconds, adding a new twist to the control and manipulation of molecules.

Yaron Silberberg

doi:10.1038/430624a


Genomes:  Worming into genetic instability p625

A study of roundworms shows that genomic mutations occur surprisingly frequently, and that the kinds of changes involved differ from those predicted. Are genomes inherently less stable than previously suspected?

Susan M. Rosenberg and P. J. Hastings

doi:10.1038/430625a


100 and 50 years ago p625

doi:10.1038/430625b


Research highlights p627

doi:10.1038/430627a


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Brief Communications

Biotechnology:  Surrogate broodstock produces salmonids p629

Trout offspring can be created from trout-donor germ cells transplanted into salmon.

Yutaka Takeuchi, Goro Yoshizaki and Toshio Takeuchi

doi:10.1038/430629a


Thin films:  Unexpected magnetism in a dielectric oxide p630

M. Venkatesan, C. B. Fitzgerald and J. M. D. Coey

doi:10.1038/430630a


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Review

Pathways towards and away from Alzheimer's disease p631

Mark P. Mattson

doi:10.1038/nature02621


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Article

Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template p640

Yong Xiong and Thomas A. Steitz

doi:10.1038/nature02711


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Letters to Nature

An apparently normal bold italic gamma-ray burst with an unusually low luminosity p646

S. Yu. Sazonov, A. A. Lutovinov and R. A. Sunyaev

doi:10.1038/nature02748

See also: News and Views by Woosley


The sub-energetic bold gamma-ray burst GRB 031203 as a cosmic analogue to the nearby GRB 980425 p648

A. M. Soderberg, S. R. Kulkarni, E. Berger, D. W. Fox, M. Sako, D. A. Frail, A. Gal-Yam, D. S. Moon, S. B. Cenko, S. A. Yost, M. M. Phillips, S. E. Persson, W. L. Freedman, P. Wyatt, R. Jayawardhana and D. Paulson

doi:10.1038/nature02757


Two-dimensional geometry of spin excitations in the high-transition-temperature superconductor YBa2Cu3O6+x p650

V. Hinkov, S. Pailhès, P. Bourges, Y. Sidis, A. Ivanov, A. Kulakov, C. T. Lin, D. P. Chen, C. Bernhard and B. Keimer

doi:10.1038/nature02774


Controlling the dynamics of spontaneous emission from quantum dots by photonic crystals p654

Peter Lodahl, A. Floris van Driel, Ivan S. Nikolaev, Arie Irman, Karin Overgaag, Daniël Vanmaekelbergh and Willem L. Vos

doi:10.1038/nature02772


Atomic-scale imaging of nanoengineered oxygen vacancy profiles in SrTiO3 p657

David A. Muller, Naoyuki Nakagawa, Akira Ohtomo, John L. Grazul and Harold Y. Hwang

doi:10.1038/nature02756

See also: News and Views by Mannhart & Schlom


Vigorous exchange between the Indian and Atlantic oceans at the end of the past five glacial periods p661

Frank J. C. Peeters, Ruth Acheson, Geert-Jan A. Brummer, Wilhelmus P. M. de Ruijter, Ralph R. Schneider, Gerald M. Ganssen, Els Ufkes and Dick Kroon

doi:10.1038/nature02785


The avian nature of the brain and inner ear of Archaeopteryx p666

Patricio Domínguez Alonso, Angela C. Milner, Richard A. Ketcham, M. John Cookson and Timothy B. Rowe

doi:10.1038/nature02706

See also: News and Views by Witmer


Processing of wild cereal grains in the Upper Palaeolithic revealed by starch grain analysis p670

Dolores R. Piperno, Ehud Weiss, Irene Holst and Dani Nadel

doi:10.1038/nature02734


Effect of trace metal availability on coccolithophorid calcification p673

K. G. Schulz, I. Zondervan, L. J. A. Gerringa, K. R. Timmermans, M. J. W. Veldhuis and U. Riebesell

doi:10.1038/nature02631


Aggression by polyembryonic wasp soldiers correlates with kinship but not resource competition p676

David Giron, Derek W. Dunn, Ian C. W. Hardy and Michael R. Strand

doi:10.1038/nature02721


High mutation rate and predominance of insertions in the Caenorhabditis elegans nuclear genome p679

Dee R. Denver, Krystalynne Morris, Michael Lynch and W. Kelley Thomas

doi:10.1038/nature02697

See also: News and Views by Rosenberg & Hastings


Optimal neural population coding of an auditory spatial cue p682

Nicol S. Harper and David McAlpine

doi:10.1038/nature02768


Sirtuin activators mimic caloric restriction and delay ageing in metazoans p686

Jason G. Wood, Blanka Rogina, Siva Lavu, Konrad Howitz, Stephen L. Helfand, Marc Tatar and David Sinclair

doi:10.1038/nature02789


Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation p689

Ying Gong, Chunhui Mo and Scott E. Fraser

doi:10.1038/nature02796


De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling p694

Ingrid E. Wertz, Karen M. O'Rourke, Honglin Zhou, Michael Eby, L. Aravind, Somasekar Seshagiri, Ping Wu, Christian Wiesmann, Rohan Baker, David L. Boone, Averil Ma, Eugene V. Koonin and Vishva M. Dixit

doi:10.1038/nature02794


Structural basis for template-independent RNA polymerization p700

Kozo Tomita, Shuya Fukai, Ryuichiro Ishitani, Takuya Ueda, Nono Takeuchi, Dmitry G. Vassylyev and Osamu Nureki

doi:10.1038/nature02712


Erratum: Single-crystal metallic nanowires and metal/semiconductor nanowire heterostructures p704

Yue Wu, Jie Xiang, Chen Yang, Wei Lu and Charles M. Lieber

doi:10.1038/nature02811


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Naturejobs

Prospects

The accidental science writer p705

Paul Smaglik

doi:10.1038/nj7000-705a


Special Report

Back to basics: from industry to academia p706

Scientists are returning from industry to academia with an eye on efficiency and applied science. Kendall Powell explores the attitude adjustments.

Kendall Powell

doi:10.1038/nj7000-706a


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