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Review
Nature 430, 631-639 (5 August 2004) | doi:10.1038/nature02621
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Postdoctoral Fellow in Immunology
- The Scripps Research Institute
- N Torrey Pines Rd, San Diego, CA, USA
Assistant Manager-Pharma / CRO-Global Strategic Sourcing
- Varda Biotech
- Mumbai India
Pathways towards and away from Alzheimer's disease
Mark P. Mattson
Abstract
Slowly but surely, Alzheimer's disease (AD) patients lose their memory and their cognitive abilities, and even their personalities may change dramatically. These changes are due to the progressive dysfunction and death of nerve cells that are responsible for the storage and processing of information. Although drugs can temporarily improve memory, at present there are no treatments that can stop or reverse the inexorable neurodegenerative process. But rapid progress towards understanding the cellular and molecular alterations that are responsible for the neuron's demise may soon help in developing effective preventative and therapeutic strategies.
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