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Nature 430, 625-626 (5 August 2004) | doi:10.1038/430625a; Published online 4 August 2004
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Genomes: Worming into genetic instability
Susan M. Rosenberg1 & P. J. Hastings1
Abstract
A study of roundworms shows that genomic mutations occur surprisingly frequently, and that the kinds of changes involved differ from those predicted. Are genomes inherently less stable than previously suspected?
DNA carries the coded information that specifies the size, shape, body plan and many other basic characteristics of most organisms. To transmit these characteristics faithfully, DNA must pass from generation to generation with relatively few mutations.
- Susan M. Rosenberg and P. J. Hastings are in the Department of Molecular and Human Genetics, and Susan M. Rosenberg is also in the Departments of Biochemistry and Molecular Biology, and Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030-3411, USA.
e-mail: Email: smr@bcm.tmc.edu
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