Table of contents
Volume 430 Number 6995 pp1-121
(this content only available online) indicates content that is available online only
Editorials
Conflicts at the NIH (cont.) p1
Previous assurances by the director of the US National Institutes of Health to Congress over the regulation of conflicts of interest are contradicted by fresh allegations. Tough new rules for staff seem essential to restore public confidence.
doi:10.1038/430001a
Risks of high winds p1
Proponents of turbines on top of New York's Freedom Tower had better get their sums right.
doi:10.1038/430001b
News
Earth science loses autonomy as NASA switches focus to the Moon p3
Tony Reichhardt
doi:10.1038/430003a
Kerry promises spectrum sale to fund science p4
Geoff Brumfiel
doi:10.1038/430004a
Increasing virulence of bird flu threatens mammals p4
Helen Pilcher
doi:10.1038/430004b
UN urged to use science in fight against food shortfall p5
Helen Pearson
doi:10.1038/430005a
Research cloning gets green light from Japanese ethicists p5
David Cyranoski
doi:10.1038/430005b
Weapons plan gives United Nations key role p6
Geoff Brumfiel
doi:10.1038/430006a
Santa Cruz brush-off leaves artists in a different class p6
Jonathan Knight
doi:10.1038/430006b
Junior biologists score partial victory over lab conditions p7
Alison Abbott
doi:10.1038/430007a
Academics seek to cast peer review as a public service p7
Declan Butler
doi:10.1038/430007b
News Features
Mario Capecchi: From rags to research p10
As a child, geneticist Mario Capecchi had to fight for survival after his mother was imprisoned by the Nazis. He tells his story to Carina Dennis, hoping to inspire others from a disadvantaged background.
doi:10.1038/430010a
Urban wind power: Breezing into town p12
The world's highest urban wind farm could be a flagship project for renewable energy, if New York City planners get their way. Are city dwellers ready for wind power? Jonathan Knight investigates.
doi:10.1038/430012a
Neuroscience: Change of mind p14
A brain haemorrhage turned an ex-convict into an obsessive artist. Jim Giles meets him and the scientists studying his case.
doi:10.1038/430014a
Correspondence
People power against climate change p15
Local government and communities needn't wait for the big players to decide on action.
Jim Gillon
doi:10.1038/430015a
Ground rules for dealing with anthropomorphism p15
Gordon M. Burghardt
doi:10.1038/430015b
Political interference not needed in Iraqi science p15
Robert May
doi:10.1038/430015c
No joke when a technical fault fools readers p15
Michael Heather
doi:10.1038/430015d
Books and Arts
The vehicle takes the wheel p17
Can our brains wrest control from our genes to put our own interests first?
Valerie M. Chase reviews The Robot's Rebellion: Finding Meaning in the Age of Darwin by Keith E. Stanovich
doi:10.1038/430017a
A chrestomathy on fishes p18
John C. Avise reviews Darwin's Fishes: An Encyclopedia of Ichthyology, Ecology and Evolution by Daniel Pauly
doi:10.1038/430018a
Infinite beauty p18
Kenneth Falconer reviews Fractals and Chaos: The Mandelbrot Set and Beyond by Benoit B. Mandelbrot
doi:10.1038/430018b
Science in culture p19
Medical drawings bring a new dimension to the Royal Academy's Summer Exhibition in London.
Martin Kemp reviews
doi:10.1038/430019a
Living machinery p20
Christof M. Niemeyer reviews Bionanotechnology: Lessons from Nature by David S. Goodsell
doi:10.1038/430020a
Essay
ConceptA model for madness? p21
Dream consciousness: our understanding of the neurobiology of sleep offers insight into abnormalities in the waking brain.
Allan Hobson
doi:10.1038/430021a
News and Views
Circadian rhythms: As time glows by in bacteria p23
Populations of cells can exhibit remarkably precise and stable circadian oscillations. But can single cells achieve such precision in the absence of intercellular communication? For cyanobacteria, it seems so.
Carl Hirschie Johnson
doi:10.1038/430023a
Extrasolar planets: Too close for comfort p24
Three gas-giant planets have now been found in puzzlingly close orbits around their stars. These 'very hot Jupiters' raise questions about planet-finding methods and our understanding of planetary systems.
Gibor Basri
doi:10.1038/430024a
Evolutionary genomics: Seeing double p25
How do genomes evolve? Studies of numerous yeast species confirm the view that the duplication of genes, larger chromosomal segments and whole genomes are key mechanisms.
André Goffeau
doi:10.1038/430025a
Palaeoclimate: Message from the fish teeth p26
An innovative analysis of isotope signatures in fish fossils will help in understanding past ocean circulation and its role in the climate system, and in testing models for climate reconstruction.
Bernhard Diekmann
doi:10.1038/430026a
Neurobiology: Sleep on it p27
Is the function of sleep to replenish energy resources or to modify neural connections in the brain? Recordings of the brain's 'reverberating circuits' evident during sleep shed light on the question.
Ilana S. Hairston and Robert T Knight
doi:10.1038/430027a
100 and 50 years ago p27
doi:10.1038/430027b
Astronomy: Where are Procyon's quakes? p29
The acoustic waves that ripple through the Sun should exist in other stars too. But a search for these 'starquakes' in the nearby star Procyon has found no evidence of them.
Jørgen Christensen-Dalsgaard and Hans Kjeldsen
doi:10.1038/430029a
Cancer: Understanding the target p30
The complicated responses of lung-cancer patients to a particular drug — gefitinib — are now less puzzling. Mutations in the target gene help to explain why the treatment works in some cases but not in others.
Michael R. Stratton and P. Andrew Futreal
doi:10.1038/430030a
Brief Communications
Pterosaurs as part of a spinosaur diet p33
A rare fossilized action snapshot captures a mortal tussle with a hungry predator.
Eric Buffetaut, David Martill and François Escuillié
doi:10.1038/430033a
First paragraph | Full Text | PDF (153K)
Top of page
Brief Communications Arising
Biodiversity conservation: Uncertainty in predictions of extinction risk
Wilfried Thuiller, Miguel B. Araújo, Richard G. Pearson, Robert J. Whittaker, Lluís Brotons and Sandra Lavorel
doi:10.1038/nature02716
First paragraph | Full Text | PDF (41K)
Biodiversity conservation: Effects of changes in climate and land use
Lauren B. Buckley and Joan Roughgarden
doi:10.1038/nature02717
First paragraph | Full Text | PDF (36K)
Biodiversity conservation: Climate change and extinction risk
John Harte, Annette Ostling, Jessica L. Green and Ann Kinzig
doi:10.1038/nature02718
First paragraph | Full Text | PDF (36K)
Biodiversity conservation: Uncertainty in predictions of extinction risk/Effects of changes in climate and land use/Climate change and extinction risk (reply)
Chris D. Thomas, Stephen E. Williams, Alison Cameron, Rhys E. Green, Michel Bakkenes, Linda J. Beaumont, Yvonne C. Collingham, Barend F. N. Erasmus, Marinez Ferreira de Siqueira, Alan Grainger, Lee Hannah, Lesley Hughes, Brian Huntley, Albert S. van Jaarsveld, Guy F. Midgley, Lera Miles, Miguel A. Ortega-Huerta, A. Townsend Peterson and Oliver L. Phillips
doi:10.1038/nature02719
First paragraph | Full Text | PDF (51K)
Articles
Genome evolution in yeasts p35
Bernard Dujon, David Sherman, Gilles Fischer, Pascal Durrens, Serge Casaregola, Ingrid Lafontaine, Jacky de Montigny, Christian Marck, Cécile Neuvéglise, Emmanuel Talla, Nicolas Goffard, Lionel Frangeul, Michel Aigle, Véronique Anthouard, Anna Babour, Valérie Barbe, Stéphanie Barnay, Sylvie Blanchin, Jean-Marie Beckerich, Emmanuelle Beyne, Claudine Bleykasten, Anita Boisramé, Jeanne Boyer, Laurence Cattolico, Fabrice Confanioleri, Antoine de Daruvar, Laurence Despons, Emmanuelle Fabre, Cécile Fairhead, Hélène Ferry-Dumazet, Alexis Groppi, Florence Hantraye, Christophe Hennequin, Nicolas Jauniaux, Philippe Joyet, Rym Kachouri, Alix Kerrest, Romain Koszul, Marc Lemaire, Isabelle Lesur, Laurence Ma, Héloïse Muller, Jean-Marc Nicaud, Macha Nikolski, Sophie Oztas, Odile Ozier-Kalogeropoulos, Stefan Pellenz, Serge Potier, Guy-Franck Richard, Marie-Laure Straub, Audrey Suleau, Dominique Swennen, Fredj Tekaia, Micheline Wésolowski-Louvel, Eric Westhof, Bénédicte Wirth, Maria Zeniou-Meyer, Ivan Zivanovic, Monique Bolotin-Fukuhara, Agnès Thierry, Christiane Bouchier, Bernard Caudron, Claude Scarpelli, Claude Gaillardin, Jean Weissenbach, Patrick Wincker and Jean-Luc Souciet
doi:10.1038/nature02579
Abstract | Full Text | PDF (579K) | Supplementary information
See also: News and Views by Goffeau
Crystal structure of a self-splicing group I intron with both exons p45
Peter L. Adams, Mary R. Stahley, Anne B. Kosek, Jimin Wang and Scott A. Strobel
doi:10.1038/nature02642
Abstract | Full Text | PDF (402K) | Supplementary information
Letters to Nature
No stellar p-mode oscillations in space-based photometry of Procyon p51
Jaymie M. Matthews, Rainer Kusching, David B. Guenther, Gordon A. H. Walker, Anthony F.J. Moffat, Slavek M. Rucinski, Dimitar Sasselov and Werner W. Weiss
doi:10.1038/nature02671
First paragraph | Full Text | PDF (233K) | Supplementary information
See also: News and Views by Christensen-Dalsgaard & Kjeldsen
Experimental demonstration of five-photon entanglement and open-destination teleportation p54
Zhi Zhao, Yu-Ao Chen, An-Ning Zhang, Tao Yang, Hans J. Briegel and Jian-Wei Pan
doi:10.1038/nature02643
First paragraph | Full Text | PDF (251K)
Cyclotron frequency shifts arising from polarization forces p58
James K. Thompson, Simon Rainville and David E. Pritchard
doi:10.1038/nature02682
First paragraph | Full Text | PDF (248K)
Single-crystal metallic nanowires and metal/semiconductor nanowire heterostructures p61
Yue Wu, Jie Xiang, Chen Yang, Wei Lu and Charles M. Lieber
doi:10.1038/nature02674
First paragraph | Full Text | PDF (1,104K)
Evidence for deep-water production in the North Pacific Ocean during the early Cenozoic warm interval p65
Deborah J. Thomas
doi:10.1038/nature02639
First paragraph | Full Text | PDF (952K)
See also: News and Views by Diekmann
Role of metal-reducing bacteria in arsenic release from Bengal delta sediments p68
Farhana S. Islam, Andrew G. Gault, Christopher Boothman, David A. Polya, John M. Charnock, Debashis Chatterjee and Jonathan R. Lloyd
doi:10.1038/nature02638
First paragraph | Full Text | PDF (170K) | Supplementary information
Why large-scale climate indices seem to predict ecological processes better than local weather p71
T. B. Hallett, T. Coulson, J. G. Pilkington, T. H. Clutton-Brock, J. M. Pemberton and B. T. Grenfell
doi:10.1038/nature02708
First paragraph | Full Text | PDF (251K)
Microbialite resurgence after the Late Ordovician extinction p75
Peter M. Sheehan and Mark T. Harris
doi:10.1038/nature02654
First paragraph | Full Text | PDF (256K)
Local sleep and learning p78
Reto Huber, M. Felice Ghilardi, Marcello Massimini and Giulio Tononi
doi:10.1038/nature02663
First paragraph | Full Text | PDF (306K)
See also: News and Views by Hairston & Knight
Resilient circadian oscillator revealed in individual cyanobacteria p81
Irina Mihalcescu, Weihong Hsing and Stanislas Leibler
doi:10.1038/nature02533
First paragraph | Full Text | PDF (490K) | Supplementary information
See also: News and Views by Johnson
Evolutionary changes in cis and trans gene regulation p85
Patricia J. Wittkopp, Belinda K. Haerum and Andrew G. Clark
doi:10.1038/nature02698
First paragraph | Full Text | PDF (280K) | Supplementary information
Evidence for dynamically organized modularity in the yeast protein–protein interaction network p88
Jing-Dong J. Han, Nicolas Bertin, Tong Hao, Debra S. Goldberg, Gabriel F. Berriz, Lan V. Zhang, Denis Dupuy, Albertha J. M. Walhout, Michael E. Cusick, Frederick P. Roth and Marc Vidal
doi:10.1038/nature02555
First paragraph | Full Text | PDF (730K) | Supplementary information
PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates p93
Xiaowei Lu, Annette G. M. Borchers, Christine Jolicoeur, Helen Rayburn, Julie C. Baker and Marc Tessier-Lavigne
doi:10.1038/nature02677
First paragraph | Full Text | PDF (544K) | Supplementary information
Nitrification by plants that also fix nitrogen p98
Charles R. Hipkin, Deborah J. Simpson, Stephen J. Wainwright and Mansour A. Salem
doi:10.1038/nature02635
First paragraph | Full Text | PDF (170K) | Supplementary information
Context-dependent contributions of backbone hydrogen bonding to 
-sheet folding energetics p101
Songpon Deechongkit, Houbi Nguyen, Evan T. Powers, Philip E. Dawson, Martin Gruebele and Jeffery W. Kelly
doi:10.1038/nature02611
First paragraph | Full Text | PDF (274K) | Supplementary information
Corrigendum: Global-scale temperature patterns and climate forcing over the past six centuries p105
Michael E. Mann, Raymond S. Bradley and Malcolm K. Hughes
doi:10.1038/nature02478
Full Text | PDF (82K) | Supplementary information
Technology Features
Drug discovery: The leading edge p109
Synthesizing and selecting the lead compounds that will become the drugs of the future are the heart of drug discovery. Tim Chapman goes back to basics.
Tim Chapman
doi:10.1038/430109a
Mining the proteome p109
doi:10.1038/430109b
Proteins on the move p111
doi:10.1038/430111a
Starting from scratch p113
doi:10.1038/430113a
Table of suppliers p117
doi:10.1038/430117a
