Supplementary information

From the following article:

Gene regulation and DNA damage in the ageing human brain

Tao Lu, Ying Pan, Shyan-Yuan Kao, Cheng Li, Isaac Kohane, Jennifer Chan and Bruce A. Yankner

Nature 429, 883-891(24 June 2004)

doi:10.1038/nature02661

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Supplementary Figure 1

Effects of limited oxidative stress and hOGG1 overexpression on cell survival.

Supplementary Figure 2

Knockdown of mitochondrial F1 ATP synthase alpha increases DNA damage.

Supplementary Table 1

Human brain samples

Supplementary Table 2

Age-regulated genes

Supplementary Table 3

Significance analysis of microarrays

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