Babies born with physical defects in their hearts may survive, but they often suffer defects in heart function as adults. The physical and functional problems might, it seems, have the same genetic cause.
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Srivastava, D. An ongoing genetic battle?. Nature 429, 819–822 (2004). https://doi.org/10.1038/429819a
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DOI: https://doi.org/10.1038/429819a