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Nature 429, 811 (24 June 2004) | doi:10.1038/429811a

Turning points Mentors and manipulation

G. J. V. Nossal1

  1. G. J. V. Nossal is in the Department of Pathology, the University of Melbourne, Victoria 3010, Australia.
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How Nobel assistance helped a young researcher test a crazy idea.

Frank Macfarlane Burnet and Joshua Lederberg, Nobel laureates of 1960 and 1958, are each giants: Burnet is the grand old man of Australian virology and immunology; Lederberg is the brilliant founder of the new discipline of bacterial genetics. During three heady months in 1957, I was the meat in their sandwich, and had the good fortune of instigating a turning point in the exciting problem of how cells make antibodies.

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