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Nature 429, 819-822 (24 June 2004) | doi:10.1038/429819a

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Heart disease:  An ongoing genetic battle?

Deepak Srivastava1

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Babies born with physical defects in their hearts may survive, but they often suffer defects in heart function as adults. The physical and functional problems might, it seems, have the same genetic cause.

Thirty years ago, children born with a heart defect had little chance of survival. Thanks to surgical and medical advances, the outlook now is usually not so grim, such that although the incidence of congenital heart disease (CHD) has not changed substantially (still nearly 1 out of every 100 live births), its prevalence is rising rapidly1.

  1. Deepak Srivastava is in the Departments of Pediatrics (Cardiology) and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center Dallas, 6000 Harry Hines Boulevard, Dallas, Texas 75390-9148, USA.
    e-mail: Email: deepak.srivastava@utsouthwestern.edu

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