Access

News and Views

Nature 429, 819-822 (24 June 2004) | doi:10.1038/429819a

Open Innovation Challenges

naturejobs

More science jobs
Post a job for free

Heart disease:  An ongoing genetic battle?

Deepak Srivastava1

Top

Babies born with physical defects in their hearts may survive, but they often suffer defects in heart function as adults. The physical and functional problems might, it seems, have the same genetic cause.

Thirty years ago, children born with a heart defect had little chance of survival. Thanks to surgical and medical advances, the outlook now is usually not so grim, such that although the incidence of congenital heart disease (CHD) has not changed substantially (still nearly 1 out of every 100 live births), its prevalence is rising rapidly1.

  1. Deepak Srivastava is in the Departments of Pediatrics (Cardiology) and Molecular Biology, University of Texas Southwestern Medical Center and Children's Medical Center Dallas, 6000 Harry Hines Boulevard, Dallas, Texas 75390-9148, USA.
    e-mail: Email: deepak.srivastava@utsouthwestern.edu

MORE ARTICLES LIKE THIS

These links to content published by NPG are automatically generated.

NEWS AND VIEWS

Getting the T-box dose right

Nature Medicine News and Views (01 Nov 2001)

Listening for hoof beats in heart beats

Nature Medicine News and Views (01 Sep 2000)

See all 3 matches for News And Views

RESEARCH

Genetic and demographic parameters determining population persistence after a discrete change in the environment

Heredity Original Article

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

Nature Genetics Article (01 Jun 1997)

See all 4 matches for Research