FIGURE 3. Interactions between PP1 and MYPT1.

a, Stereo diagram of the interactions between the N-terminal arm of MYPT1 (green carbon atoms) and PP1 (yellow carbon atoms). b, The same region of MYPT1 superimposed onto an electrostatic surface representation of PP1, where red, blue and white indicate negatively-charged, positively-charged and non-charged regions, respectively. c, Stereo diagram of the interactions involving the RVxF motif and the first -helix of ankyrin repeat 1. d, The same region of MYPT1 superimposed onto an electrostatic surface representation of PP1. Note that the basic sequence preceding the RVxF motif does not interact directly with the acidic patch at the lower right corner of this figure.