Provider: Nature Publishing Group Content: application/x-research-info-systems TY - JOUR AU - Clancy, D. J. TI - Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein JO - Science PY - 2001/// VL - 292 SP - 104 EP - 106 M3 - 10.1126/science.1057991 N1 - 10.1126/science.1057991 UR - http://dx.doi.org/10.1126/science.1057991 ER - TY - JOUR AU - Tu, M.-P. AU - Epstein, D. AU - Tatar, M. TI - The demography of slow aging in male and female Drosophila mutant for the insulin-receptor substrate homolog chico JO - Aging Cell PY - 2002/// VL - 1 SP - 75 EP - 80 M3 - 10.1046/j.1474-9728.2002.00010.x N1 - 10.1046/j.1474-9728.2002.00010.x UR - http://dx.doi.org/10.1046/j.1474-9728.2002.00010.x ER - TY - JOUR AU - Tatar, M. TI - A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function JO - Science PY - 2001/// VL - 292 SP - 107 EP - 110 M3 - 10.1126/science.1057987 N1 - 10.1126/science.1057987 UR - http://dx.doi.org/10.1126/science.1057987 ER - TY - JOUR AU - Dillin, A. AU - Crawford, D. K. AU - Kenyon, C. TI - Timing requirements for insulin/IGF-1 signaling in C. elegans JO - Science PY - 2002/// VL - 298 SP - 830 EP - 834 M3 - 10.1126/science.1074240 N1 - 10.1126/science.1074240 UR - http://dx.doi.org/10.1126/science.1074240 ER - TY - JOUR AU - Libina, N. AU - Berman, J. R. AU - Kenyon, C. TI - Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan JO - Cell PY - 2003/// VL - 115 SP - 489 EP - 502 M3 - 10.1016/S0092-8674(03)00889-4 N1 - 10.1016/S0092-8674(03)00889-4 UR - http://dx.doi.org/10.1016/S0092-8674(03)00889-4 ER - TY - JOUR AU - Kenyon, C. AU - Chang, J. AU - Gensch, E. AU - Rudner, A. AU - Tabtiang, R. TI - A C. elegans mutant that lives twice as long as wild type JO - Nature PY - 1993/// VL - 366 SP - 461 EP - 464 M3 - 10.1038/366461a0 N1 - 10.1038/366461a0 UR - http://dx.doi.org/10.1038/366461a0 ER - TY - JOUR AU - Puig, O. AU - Marr, M. T. AU - Ruhf, M. L. AU - Tjian, R. TI - Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway JO - Genes Dev. PY - 2003/// VL - 17 SP - 2006 EP - 2020 M3 - 10.1101/gad.1098703 N1 - 10.1101/gad.1098703 UR - http://dx.doi.org/10.1101/gad.1098703 ER - TY - GEN PY - /// ER - TY - JOUR AU - Roman, G. AU - Endo, K. AU - Zong, L. AU - Davis, R. L. TI - P[lcub]Switch[rcub], a system for spatial and temporal control of gene expression in Drosophila melanogaster JO - Proc. Natl Acad. Sci. USA PY - 2001/// VL - 98 SP - 12602 EP - 12607 M3 - 10.1073/pnas.221303998 N1 - 10.1073/pnas.221303998 UR - http://dx.doi.org/10.1073/pnas.221303998 ER - TY - JOUR AU - Osterwalder, T. AU - Yoon, K. S. AU - White, B. H. AU - Keshishian, H. TI - A conditional tissue-specific transgene expression system using inducible GAL4 JO - Proc. Natl Acad. Sci. USA PY - 2001/// VL - 98 SP - 12596 EP - 12601 M3 - 10.1073/pnas.221303298 N1 - 10.1073/pnas.221303298 UR - http://dx.doi.org/10.1073/pnas.221303298 ER - TY - JOUR AU - Dobens, L. L. TI - The Drosophila bunched gene is a homologue of the growth factor stimulated mammalian TSC-22 sequence and is required during oogenesis JO - Mech. Dev. PY - 1997/// VL - 65 SP - 197 EP - 208 M3 - 10.1016/S0925-4773(97)00080-4 N1 - 10.1016/S0925-4773(97)00080-4 UR - http://dx.doi.org/10.1016/S0925-4773(97)00080-4 ER - TY - JOUR AU - Tatar, M. AU - Bartke, A. AU - Antebi, A. TI - The endocrine regulation of aging by insulin-like signals JO - Science PY - 2003/// VL - 299 SP - 1346 EP - 1351 M3 - 10.1126/science.1081447 N1 - 10.1126/science.1081447 UR - http://dx.doi.org/10.1126/science.1081447 ER - TY - JOUR AU - Ashrafi, K. TI - Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes JO - Nature PY - 2003/// VL - 421 SP - 268 EP - 272 M3 - 10.1038/nature01279 N1 - 10.1038/nature01279 UR - http://dx.doi.org/10.1038/nature01279 ER - TY - JOUR AU - Garofalo, R. S. TI - Genetic analysis of insulin signaling in Drosophila JO - Trends Endocrinol. Metab. PY - 2002/// VL - 13 SP - 156 EP - 162 M3 - 10.1016/S1043-2760(01)00548-3 N1 - 10.1016/S1043-2760(01)00548-3 UR - http://dx.doi.org/10.1016/S1043-2760(01)00548-3 ER - TY - JOUR AU - Rulifson, E. J. AU - Kim, S. K. AU - Nusse, R. TI - Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes JO - Science PY - 2002/// VL - 296 SP - 1118 EP - 1120 M3 - 10.1126/science.1070058 N1 - 10.1126/science.1070058 UR - http://dx.doi.org/10.1126/science.1070058 ER - TY - JOUR AU - Cao, C. AU - Brown, M. R. TI - Localization of an insulin-like peptide in brains of two flies JO - Cell Tissue Res. PY - 2001/// VL - 304 SP - 317 EP - 321 M3 - 10.1007/s004410100367 N1 - 10.1007/s004410100367 UR - http://dx.doi.org/10.1007/s004410100367 ER - TY - JOUR AU - Brogiolo, W. TI - An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control JO - Curr. Biol. PY - 2001/// VL - 11 SP - 213 EP - 221 M3 - 10.1016/S0960-9822(01)00068-9 N1 - 10.1016/S0960-9822(01)00068-9 UR - http://dx.doi.org/10.1016/S0960-9822(01)00068-9 ER - TY - JOUR AU - Wolkow, C. A. AU - Kimura, K. D. AU - Lee, M.-S. AU - Ruvkun, G. TI - Regulation of C. elegans life-span by insulin-like signaling in the nervous system JO - Science PY - 2000/// VL - 290 SP - 147 EP - 150 M3 - 10.1126/science.290.5489.147 N1 - 10.1126/science.290.5489.147 UR - http://dx.doi.org/10.1126/science.290.5489.147 ER - TY - JOUR AU - Bluher, M. AU - Kahn, B. B. AU - Kahn, R. C. TI - Extended longevity in mice lacking the insulin receptor in adipose tissue JO - Science PY - 2003/// VL - 299 SP - 572 EP - 574 M3 - 10.1126/science.1078223 N1 - 10.1126/science.1078223 UR - http://dx.doi.org/10.1126/science.1078223 ER - TY - JOUR AU - Bluher, M. TI - Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance JO - Dev. Cell PY - 2002/// VL - 3 SP - 25 EP - 38 M3 - 10.1016/S1534-5807(02)00199-5 N1 - 10.1016/S1534-5807(02)00199-5 UR - http://dx.doi.org/10.1016/S1534-5807(02)00199-5 ER - TY - JOUR AU - Simon, A. F. AU - Shih, C. AU - Mack, A. AU - Benzer, S. TI - Steroid control of longevity in Drosophila melanogaster JO - Science PY - 2003/// VL - 299 SP - 1407 EP - 1410 M3 - 10.1126/science.1080539 N1 - 10.1126/science.1080539 UR - http://dx.doi.org/10.1126/science.1080539 ER - TY - JOUR AU - Gerisch, B. AU - Weitzel, C. AU - Kober-Eisermann, C. AU - Rottiers, V. AU - Antebi, A. TI - A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span JO - Dev. Cell PY - 2001/// VL - 1 SP - 841 EP - 851 M3 - 10.1016/S1534-5807(01)00085-5 N1 - 10.1016/S1534-5807(01)00085-5 UR - http://dx.doi.org/10.1016/S1534-5807(01)00085-5 ER - TY - JOUR AU - Jia, K. AU - Albert, P. S. AU - Riddle, D. L. TI - DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity JO - Development PY - 2002/// VL - 129 SP - 221 EP - 231 ER - TY - JOUR AU - Murphy, C. T. TI - Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans JO - Nature PY - 2003/// VL - 424 SP - 277 EP - 284 M3 - 10.1038/nature01789 N1 - 10.1038/nature01789 UR - http://dx.doi.org/10.1038/nature01789 ER - TY - JOUR AU - Saucedo, L. J. TI - Rheb promotes cell growth as a component of the insulin/TOR signaling network JO - Nature Cell Biol. PY - 2003/// VL - 5 SP - 566 EP - 571 M3 - 10.1038/ncb996 N1 - 10.1038/ncb996 UR - http://dx.doi.org/10.1038/ncb996 ER - TY - JOUR AU - Vellai, T. TI - Influence of TOR kinase on lifespan in C. elegans JO - Nature PY - 2003/// VL - 426 SP - 620 EP - 620 M3 - 10.1038/426620a N1 - 10.1038/426620a UR - http://dx.doi.org/10.1038/426620a ER -