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Nature 429, 515-517 (3 June 2004) | doi:10.1038/429515a
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Neurobiology: A matter of balance
Martyn Goulding1
Abstract
The types of chemical signal that a neuron synthesizes and communicates with were thought to be genetically encoded and largely invariable. It seems, though, that if a neuron's activity changes, so too do its signals.
Nerve cells use chemical signals known as neurotransmitters to communicate with each other. These molecules come in many different flavours, and the combination of flavours used by any given neuron represents a key property that determines not only its function within a circuit, but also the circuit's overall output.
- Martyn Goulding is in the Molecular Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.
Email: goulding@salk.edu
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