Some parasites evade the immune response of their victim by changing their antigenic coat. Surprisingly, it seems that the trick works best if the new coat isn't completely different from the old one.
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Antia, R., Koella, J. Parasitic turncoat. Nature 429, 511–513 (2004). https://doi.org/10.1038/429511a
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DOI: https://doi.org/10.1038/429511a
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Overloading the immunity of the mosquito Anopheles gambiae with multiple immune challenges
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