Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Genomic imprinting

Mice without a father

In mammals, genomes from both parents are generally needed to make viable offspring. But changing the expression of ‘imprinted’ genes can render the father's contribution dispensable.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: No need for males?

References

  1. Kono, T. et al. Nature 428, 860–864 (2004).

    Article  ADS  CAS  Google Scholar 

  2. Surani, M. A., Baron, S. C. & Norris, M. L. Nature 308, 548–550 (1984).

    Article  ADS  CAS  Google Scholar 

  3. Barton, S. C., Surani, M. A. & Norris, M. L. Nature 311, 374–376 (1984).

    Article  ADS  CAS  Google Scholar 

  4. Thorvaldsen, J. L., Duran, K. L. & Bartolomei, M. S. Genes Dev. 12, 3693–3702 (1998).

    Article  CAS  Google Scholar 

  5. Arney, K. L. Trends Genet. 19, 17–23 (2003).

    Article  CAS  Google Scholar 

  6. Kono, T., Obata, Y., Yoshimizu, T., Nakahara, T. & Carroll, J. Nature Genet. 13, 91–94 (1996).

    Article  CAS  Google Scholar 

  7. Kono, T., Sotomaru, Y., Katsuzawa, Y. & Dandolo, L. Dev. Biol. 243, 294–300 (2002).

    Article  CAS  Google Scholar 

  8. Ripoche, M. A., Kress, C., Poirier, F. & Dandolo, L. Genes Dev. 11, 1596–1604 (1997).

    Article  CAS  Google Scholar 

  9. Leighton, P. A., Ingram, R. S., Eggenschwiler, J., Efstratiadis, A. & Tilghman, S. M. Nature 375, 34–39 (1995).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Loebel, D., Tam, P. Mice without a father. Nature 428, 809–811 (2004). https://doi.org/10.1038/428809a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/428809a

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing