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Nature 428, 607-608 (8 April 2004) | doi:10.1038/nature02500; Published online 21 March 2004

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Stem cells: Lost in translation

Kenneth R. Chien1

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The potential use of stem cells as agents of repair in human disease makes them the subject of high-profile studies. But we should be wary of prematurely pushing laboratory research into clinical practice.

On the road map for 'translational medicine' — often referred to as bench-to-bedside research — stem-cell therapy is a prime destination. Stem cells are cells that have not taken on the identity of any specific cell type and are not yet committed to any dedicated function; they can divide indefinitely and may be induced to give rise to one or more specialized cell types.

  1. Kenneth R. Chien is at the Institute of Molecular Medicine, University of California, San Diego, La Jolla, California 92093, USA.
    Email: kchien@ucsd.edu

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